Relationship of Helicobacter Pylori Specific IgG Antibodies with Serum Magenisum and Serum Lipid Profile in Patients on Maintenance Hemodialysis

Abstract

Background: Helicobacter pylori are thought to play an important role in the pathogenesis of activegastritis and other upper mucosal lesions in chronic hemodialysis patient which thoughtto result in dyspeptic symptoms. Aim:The aim of the study is to determine the prevalence of Helicobacter pylori infection in patient on maintenance hemodialysis and to assess the probable association of serum lipid profile and serum magnesium with H. pylori infection in these patients. Material &Methods: This cross-sectional study was conducted on patients with end stage renal disease who were undergoing maintenance hemodialysis treatment.were enrolled in the present studya total number of 42 hemodialysis patients (24 male and 18 female), of the total number; 10 were diabetic and 32 were non diabetic. Demographic data including age, gender, duration of hemodialysis and clinical data including diabetes mellitus, upper gastrointestinal symptoms and laboratory measurements were obtained from related questionnaires. Venous blood samples were collected for biochemical analysis of the following markers: serum magnesium, total cholesterol, triglyceride; high density lipoprotein-cholesterol, low density lipoprotein-cholesterol and very low density lipoprotein-cholesterol. Result & Conclusion: We conclude that there was no significant correlation between gender, age, duration of hemodialysis, DM, serum triglyceride, VLDL-C and magnesium and H. pylori infection in these patients.