Aspects Of Integration Research Articles

СОВРЕМЕННЫЙ КОНТРОЛЬ КАЧЕСТВА ОНКОЛОГИЧЕСКОЙ ПОМОЩИ СОПРЯЖЕН С РАЗВИТИЕМ МЕДИЦИНСКОЙ ИНФОРМАТИКИ

Quality control is an integral aspect of the functioning of the medical industry. There is an increase in demand for cancer care worldwide, which is subject to new requirements. At the same time, the concept of a high-quality system of oncological care includes: accessibility, timeliness, efficiency, safety, patient orientation, etc. Compliance with these requirements is impossible without the widespread use of medical informatic sistems . The development of medical informatics has led to the digitalization of technologies for managing the organization of internal quality control of oncological care to the population. The presented material reflects innovative approaches to automated assessments of the quality of cancer care. The search was conducted in the PubMed (Medline) database. In the search bar, queries were entered (“oncology”, “cancer”, “cancer treatment”, “oncology informatics”, “clinical audit”, etc.) on the topic of quality control of treatment of patients with ZNO using medical informatics tools. The material combines data from 18 sources. The creation of an information base, the variety of information entered, the use of big data processing principles, all this opens up additional opportunities for assessing the quality of cancer care. It is necessary to widely introduce innovative automated systems for the development and implementation of multi-criteria assessments of the quality of work of the oncological service. The integration of sources and means of technical support and information processing into a single information and digital circuit is a key condition for the establishment of a system of continuous automated monitoring of the quality of oncological care in real time.

Structure Design and Strength Analysis of the Glass Reinforcement Plastic (GRP) Malay Traditional “Perahu Bedar”

The Perahu Bedar, a traditional fishing boat in the Terengganu region of Malaysia, has been historically crafted from Cengal wood. In response to challenges posed by wood scarcity and limitations in skilled craftsmen, this study pioneers the exploration of Glass Reinforced Plastic (GRP) as a novel alternative material for constructing the traditional Perahu Bedar, measuring 4.32 meters in length. Through a rigorous analysis, the research delves into the structural design intricacies and strength attributes of the GRP Perahu Bedar, marking a significant departure from conventional wood-based construction methods. The study conducts a comprehensive analysis of the structure design and strength characteristics of the GRP Perahu Bedar. The weight, buoyancy force, and load distribution along the boat are analyzed. The data shows varying weight and buoyancy forces along the stations, with positive load values indicating upward forces contributing to buoyancy and negative load values representing downward forces. This analysis provides insights into the boat’s stability and distribution of forces. The sheer force and bending moment along the Perahu Bedar are evaluated. The sheer force values gradually increase or decrease along the boat, while the bending moment is highest at the midsection and decreases towards the ends. These results indicate the distribution of forces and stress on the boat’s structure, aiding in understanding its integrity and stability. The Factor of Safety (FoS) analysis demonstrates a FoS value of 2.2368, indicating a safety margin greater than 1. This suggests that the GRP Perahu Bedar design meets safety requirements and can withstand applied 
 
 stresses without exceeding yield strength. The FoS value provides assurance of structural integrity and safety during normal operating conditions. In summary, this study underscores the groundbreaking potential of Glass Reinforced Plastic (GRP) as a viable alternative to traditional wooden Perahu Bedar due to very high cost of Cengal Wood (wood that been used to build Peahu Bedar). By meticulously analyzing critical factors such as weight, buoyancy, load, shear force, bending moment, and Factor of Safety (FoS), the research offers invaluable insights into the structural integrity and safety aspects of GRP Perahu Bedar. These revelations not only herald a new era of sustainable and cost-effective boatbuilding practices but also serve as a crucial step towards safeguarding and perpetuating the rich maritime heritage of the region.

LITERARY WORKS AS THE MOST IMPORTANT AND WELL-ACCLAIMED COMPONENTS OF THE CULTURAL HERITAGE OF THE NATION

This article delves into the multifaceted realm of literary work, emphasizing its traditional, oral, and communal nature. It explores the diverse components of folklore encompassing beliefs, customs, expressions, and practices shared within various cultural groups. The piece highlights the dynamic nature of folklore, which evolves through repetition, variation, and adaptation while retaining significance and continuity for the collective identity of communities. Through the lens of various folklorists' perspectives, it challenges stereotypes and misconceptions about folklore, portraying it as a living, integral aspect of contemporary life across different cultural landscapes. The article underscores the significance of folklore in preserving cultural heritage, fostering collective identity, and illuminating the universal human experience.

Вопросы развития межкультурной коммуникации студентов в процессе глобализации высшего образования

The article considers global trends of higher education, the impact of academic exchanges between countries on the development and effectiveness of reforms in this field. It also analyzes the necessity of entering the process of deep international integration of higher education, the fact that academic exchanges in the context of globalization have created the need for the development of intercultural communicative competence among students, as well as the functions of its development. The integrative, axiological, psychological and organizational aspects of pedagogical activity are analyzed.

THE SPECIFICS OF THE DEVELOPMENT OF THE FUNDAMENTAL SOCIAL INSTITUTION OF THE STATE IN THE 21ST CENTURY (ON THE EXAMPLE OF RUSSIA AND BELARUS)

The article deals with topical issues of sovereignty, integration and security of such a fundamental social institution as the state. This issue is considered on a specific material, namely, such states as Russia and Belarus are analyzed. The article shows the aspects of integration of the above-mentioned countries based on the principle of social justice. The author postulates the need to strengthen national security in the light of foreign policy threats. As the author emphasizes, cooperation between the Russian Federation and the Republic of Belarus plays an important role in ensuring security. In the light of this interaction, 28 union programs are being implemented, examples of which are discussed in the article. The author concludes about the specifics of the state development of the two friendly countries, this specificity is predetermined by the strategy of union integration

Analysis of the Potential Economic Sectors on Poverty in Malang District and Madiun District

Development is an ongoing process embraced by nearly all nations globally, as it constitutes an integral aspect of a nation's pursuit of progress. The objectives of this research are delineated as follows: Firstly, to identify the fundamental sectors in Madiun Regency and Malang Regency. Secondly, to ascertain the sectors propelling growth in other regions within Madiun Regency and Malang Regency. Thirdly, to discern which sectors are experiencing accelerated growth rates in both regions. Fourthly, to determine sectors exhibiting specialization or locational advantages in Madiun Regency and Malang Regency. Lastly, to classify the economic growth within Madiun Regency and Malang Regency. Employing a descriptive-quantitative analysis method, this research provides an overview or description of the variables associated with the phenomenon under study. The findings of this research demonstrate a significant influence of the Basic Sector on poverty levels. Additionally, the coefficient of determination value, at 65.7%, corroborates the contribution of independent variables in elucidating variations in poverty levels.

Finite Mixtures of Latent Trait Analyzers With Concomitant Variables for Bipartite Networks: An Analysis of COVID-19 Data

Networks consist of interconnected units, known as nodes, and allow to formally describe interactions within a system. Specifically, bipartite networks depict relationships between two distinct sets of nodes, designated as sending and receiving nodes. An integral aspect of bipartite network analysis often involves identifying clusters of nodes with similar behaviors. The computational complexity of models for large bipartite networks poses a challenge. To mitigate this challenge, we employ a Mixture of Latent Trait Analyzers (MLTA) for node clustering. Our approach extends the MLTA to include covariates and introduces a double EM algorithm for estimation. Applying our method to COVID-19 data, with sending nodes representing patients and receiving nodes representing preventive measures, enables dimensionality reduction and the identification of meaningful groups. We present simulation results demonstrating the accuracy of the proposed method.

A Comprehensive Analysis of the Effectiveness of Large Language Models as Automatic Dialogue Evaluators

Automatic evaluation is an integral aspect of dialogue system research. The traditional reference-based NLG metrics are generally found to be unsuitable for dialogue assessment. Consequently, recent studies have suggested various unique, reference-free neural metrics that better align with human evaluations. Notably among them, large language models (LLMs), particularly the instruction-tuned variants like ChatGPT, are shown to be promising substitutes for human judges. Yet, existing works on utilizing LLMs for automatic dialogue evaluation are limited in their scope in terms of the number of meta-evaluation datasets, mode of evaluation, coverage of LLMs, etc. Hence, it remains inconclusive how effective these LLMs are. To this end, we conduct a comprehensive study on the application of LLMs for automatic dialogue evaluation. Specifically, we analyze the multi-dimensional evaluation capability of 30 recently emerged LLMs at both turn and dialogue levels, using a comprehensive set of 12 meta-evaluation datasets. Additionally, we probe the robustness of the LLMs in handling various adversarial perturbations at both turn and dialogue levels. Finally, we explore how model-level and dimension-level ensembles impact the evaluation performance. All resources are available at https://github.com/e0397123/comp-analysis.

Exploring the Impact of Buddhist Tourism and Pilgrimage on Cultural Exchange and Understanding: An Empirical Analysis

Buddhist tourism and pilgrimage are integral aspects of cultural and spiritual exploration, serving as bridges that connect individuals, communities, and nations. This empirical study employs a mixed-method approach, integrating surveys, interviews, and observational data, to investigate the profound impact of these journeys on promoting Buddhist understanding and facilitating cultural exchange. Through the analysis of participant experiences across diverse destinations, our study unveils the transformative nature of Buddhist tourism and pilgrimage. Participants reported significant personal growth and spiritual enrichment, indicating that these journeys serve as catalysts for deepening individual spirituality. Furthermore, our findings highlight the pivotal role of these experiences in fostering cross-cultural dialogue and promoting mutual respect among diverse communities. Participants described meaningful interactions with individuals from unfamiliar cultural backgrounds, leading to a greater appreciation and understanding of cultural diversity. Moreover, Buddhist tourism and pilgrimage emerge as platforms for fostering global harmony and enlightenment. By facilitating encounters between people of various beliefs and backgrounds, these journeys contribute to the promotion of peace and understanding on a broader scale. Participants reported a heightened sense of interconnectedness with humanity and a renewed commitment to promoting compassion and tolerance in their communities. The implications of our findings extend beyond individual experiences to encompass broader societal benefits. Effective tourism management practices can leverage the transformative potential of Buddhist tourism and pilgrimage to promote sustainable development and cultural preservation in destination regions. Furthermore, our study underscores the importance of fostering interfaith dialogue and cooperation as essential components of global peace-building efforts. Buddhist tourism and pilgrimage play vital roles in promoting cultural exchange, fostering understanding, and contributing to global harmony. By recognizing and harnessing the transformative power of these journeys, stakeholders can cultivate a more interconnected and compassionate world, grounded in mutual respect and appreciation for cultural diversity.

Crisis, corruption and state-led development in the making of the Mexican drug trade

Abstract The state of Durango has long been a centre of Mexican heroin production and an important node in transnational drug trafficking networks. As early as 1944, it was the site of one of the biggest drug busts in Mexican history, when an opium poppy plantation the size of 325 football pitches, irrigated by a purpose-built aqueduct, was discovered in the state’s northern mountains. By the mid 1970s, a combination of kinship ties and concrete connected these poppy fields directly with the US drug market hub of Chicago, Illinois, along a route known as the ‘heroin highway’, which helped Mexico become the supplier of 90 per cent of US heroin. But how did a poor, underpopulated and overwhelmingly rural state become a major player in the billion-dollar US–Mexican drug trade? This article shows that in Durango, the rise of heroin production and trafficking were integral aspects of local processes of social, political and economic modernization. Stimulated by the Mexican and US governments’ promotion of infrastructural improvements and mass migration, and protected by representatives of Mexico’s post-revolutionary political system, the drug trade in turn fuelled further ‘licit’ economic development, making it part of the very foundation of Mexico as we know it today.

Abstract 4452: The macropinosome: Uncovering the molecular anatomy of an oncogene-driven organelle

Abstract As an integral aspect of the metabolic reprogramming that occurs in cancer, oncogenic KRAS mutations drive the stimulation of macropinocytosis, a type of endocytosis that mediates nonselective fluid-phase uptake. Using KRAS-driven models of pancreatic ductal adenocarcinoma (PDAC), we were the first to demonstrate that macropinocytosis functions in tumor cells as a nutrient acquisition pathway. Macropinocytosis triggers the internalization of extracellular proteins via discrete endocytic vesicles called macropinosomes. The incoming protein cargo is targeted for lysosome-dependent degradation, causing the intracellular release of amino acids. These protein-derived amino acids support metabolic fitness by contributing to the intracellular amino acid pools, as well as to the biosynthesis of central carbon metabolites. In this way, macropinocytosis represents a novel amino acid supply route that tumor cells use to survive the nutrient-poor conditions of the tumor microenvironment. While the tenets of the signal transduction events that drive macropinocytosis in cancer have emerged, a detailed picture of the macropinosome itself is not yet available. With the aid of nanotechnology, we have developed a methodology to isolate a pure fraction of macropinosomes from PDAC cells. Using a large-scale proteomic approach, we have been able to generate a list of proteins that reside in macropinosomes. The specificity of this approach was confirmed through the identification and validation of proteins known to specifically localize to these organelles in different contexts, such as Rab5 or SDC1. Thanks to this innovative method, we have demonstrated the involvement of two calcium channels, ATP2B1 and ATP2B4, in the formation of macropinosomes. By elucidating the molecular anatomy of KRAS-driven macropinosomes, we will gain further insight into the regulation and function of macropinocytosis in cancer. Moreover, having a clearer picture of the macropinosome will make us better positioned to exploit this pathway therapeutically and deliver breakthroughs to patients. Citation Format: Ambroise Manceau, Koen M. Galenkamp, Cheska M. Galapate, Cosimo Commisso. The macropinosome: Uncovering the molecular anatomy of an oncogene-driven organelle [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4452.

Shaping Social Media Minds: Scaffolding Empathy in Digitally Mediated Interactions?

Empathy is an integral aspect of human existence. Without at least a basic ability to access others’ affective life, social interactions would be well-nigh impossible. Yet, recent studies seem to show that the means we have acquired to access others’ emotional life no longer function well in what has become our everyday business – technologically mediated interactions in digital spaces. If this is correct, there are two important questions: (1) What makes empathy for frequent internet users so difficult? and (2) What can we do to alleviate the negative consequences? Correspondingly, the aim of this paper is twofold. First, we identify structural differences between offline and technologically mediated interactions that can explain why digital empathy is harder to achieve. Second, drawing on the literature on ‘situated affectivity,’ we consider the idea of modifying digital spaces in ways specifically designed to ‘scaffold’ empathy where our evolved mechanisms fail. Section 2 argues that empathy is requires interpreting the behavior of embodied subjects. Section 3 identifies three factors that are crucial for this interpretative endeavor: the empathizer’s affective repertoire, their perceptual input, and their background knowledge. Section 4 argues that technologically mediated interactions differ from face-to-face interactions with regard to these factors in ways which render our evolved empathy mechanisms less effective in the digital world. Section 5 introduces the idea that situational factors can serve as ‘empathic scaffolds,’ i.e., as ‘tools’ that can ‘shape’ people’s empathic reactions. Section 6 wraps up the main line of reasoning, responds to objections and invites further scholarship.

Crucial postulates of integration and social inclusion of representatives of the generation of locals with «migrational background»: triggers and remedies

While analyzing crucial aspect of integration and social inclusion, we are tended to underestimate representatives of special generations, which are supposed to be “automatically included and integrated”. We expect that someone, born to parents living permanently on the territory of the given country, will be fully adapted and naturally included into the outer community. The general desire to belong to this social community or another postulates the same requirements. However, in many situations, the person’s disposition to be integrated, adapted and socially included does not depend exceptionally on his/her desire, or even efforts to be “a member of a great society”. Sometimes, however, grand societal processes, prejudices and biases may block the necessary integration and social inclusion of people possessing foreigners’ backgrounds, even though they consequently are blocking multiple areas of social, societal, economical and general development of their community.

Floating Solar Materials and their Devices for Energy Conversion and Environment Remediation

AbstractFloating solar materials and their devices, which can effectively solve the problems faced by powder solar materials, such as difficult recycling, poor stability, and difficult maintenance, have received widespread attention in recent years. However, it is still in the early stage of development and still faces many challenges in material design, device preparation, and systematic application. Therefore, it is particularly necessary to summarize the research progress of related aspects to promote the development of this field (To achieve large‐scale applications, it is necessary to develop devices that can be applied on a large scale). In this review, the systematic construction methods of floating materials are reviewed from the aspects of lightweight carrier integration as well as functionalization and surface modification. Subsequently, the recent studies on floating solar materials and their devices are categorized and summarized. Their applications in the purification of polluted seawater, water splitting, CO2 reduction, and prevention of water bloom are reviewed in detail. Finally, the outlook for future development is critically discussed.

A power dispatch allocation strategy to produce green hydrogen in a grid-integrated offshore hybrid energy system

A dedicated grid-tied offshore hybrid energy system for hydrogen production is a promising solution to unlock the full benefit of offshore wind and solar energy and realize decarbonization and sustainable energy security targets in electricity and other sectors. Current knowledge of these offshore hybrid systems is limited, particularly in the integration, component control, and allocation aspects. Therefore, a grid-integrated analytical model with a power dispatch allocation strategy between the grid and electrolyzer for the co-production of hydrogen from the offshore hybrid energy system is developed in this paper. While producing hydrogen, the proposed offshore hybrid energy system supplies a percentage of its capacity to the onshore grid facility, and the amount of the electricity is quantified based on the electricity market price and available total offshore generation. The detailed controls of each component are discussed. A case study considers a hypothetical hybrid offshore energy system of 10 MW situated in a potential offshore off the NSW of Australia based on realistic metrological data. A grid-scale proton-exchange membrane electrolyzer stack is used and a model predictive power controller is implemented on the distributed hydrogen generation scheme. The model is helpful for the assessment or optimization of both the economics and feasibility of the dedicated offshore hybrid energy farm for hydrogen production systems.

ENGAGING ADOLESCENTS IN FAMILY THERAPY: THE ROLE OF ENGLISH SLANG AND DIGITAL COMMUNICATION NORMS IN THERAPEUTIC SETTINGS

ABSTRACT
 Adolescence is a critical stage marked by rapid cognitive, emotional, and social development, often presenting challenges within familial relationships. Family therapy serves as a vital intervention to address these challenges, yet engaging adolescents in the therapeutic process can be complex. This review explores the significance of English slang and digital communication norms in facilitating rapport and effective communication between therapists and adolescents in family therapy settings. In contemporary society, English slang and digital communication have become integral aspects of adolescent culture. Adolescents frequently employ slang terms and digital platforms to express themselves, communicate with peers, and navigate their identities. However, these informal modes of communication may pose barriers in traditional therapeutic settings where formal language is often prioritized. Recognizing the importance of meeting adolescents on their own communicative terms, therapists are increasingly integrating slang and digital communication norms into family therapy sessions. By incorporating familiar language and mediums, therapists can create a more inclusive and relatable environment, fostering trust and engagement with adolescent clients. Moreover, the utilization of slang and digital communication norms in family therapy promotes authenticity and enhances the therapeutic alliance between adolescents and therapists. Adolescents feel understood and validated when therapists demonstrate an awareness and acceptance of their linguistic and technological preferences, leading to increased participation and investment in the therapeutic process. However, the integration of slang and digital communication in family therapy requires careful consideration and ethical awareness. Therapists must balance the use of informal language with maintaining professional boundaries and respect for cultural diversity. Additionally, therapists should remain mindful of the potential implications of digital communication, including privacy concerns and the blurring of therapeutic boundaries. Understanding and incorporating English slang and digital communication norms are essential for effectively engaging adolescents in family therapy. By embracing adolescents' preferred modes of expression, therapists can foster meaningful connections, facilitate communication, and promote positive therapeutic outcomes within the familial context.
 Keywords: Adolescent, Family, Therapy, Slang, Digital, Communication, Norm, English.

The Role of Social Media in Facilitating Immigrant Integration into American Society

The United States, a melting pot of cultures and ethnicities, faces the ongoing challenge of integrating a diverse population of immigrants into its communities. Recent studies highlight the pivotal role of social media in this integration process, yet there remains a gap in understanding how social media usage correlates with the broader spectrum of immigrant integration. This research explores the impact of social media on facilitating essential aspects of integration for immigrants, such as language acquisition, cultural adaptation, and the development of social networks. Through an in-depth analysis, this study illustrates the critical role social media plays in helping immigrants navigate and assimilate into American society, offering insights into its potential as a tool for fostering community connections and cultural competency. The findings suggest that social media is not just a platform for socializing but a significant facilitator of the integration process, providing immigrants with the resources and support needed to become active, engaged members of their new communities.

A comprehensive approach for hydrogen production from crude glycerol: Process synthesis, energy integration, and storage

This study presents a comprehensive technique for the production of hydrogen (H2), storage of H2, and energy integration aspects in a single synthesis frame. The crude glycerol, which is derived from waste sources, is being used as a raw material for the production of H2, with the implementation of Aspen Plus software. To further resolve the storage issues, H2 is converted to methanol (CH3OH). The initial crude glycerol undergoes a series of unit operations and processes, such as saponification, acidification, and distillation, to transform it into purified glycerol. Then, using glycerol steam reforming, the generated glycerol is combined with steam to produce H2, where 68 mol% of H2 is produced. The storage and transportation of H2 is a crucial undertaking for several industries. To address this challenge, a unique strategy involves the conversion of H2 into CH3OH through a series of processes, including compression, methanation, and fractionation. Further, a comprehensive evaluation of the entire process is conducted from the perspective of process integration. The design of a heat integration network is customized to each production process. Two key factors—flow and cost—determine the net energy savings. The analysis reveals that 41.44 % of utilities achieve savings based on flow, while 14.24 % achieve savings based on cost.

The generalized telegraph equation with moving harmonic source: Solvability using the integral decomposition technique and wave aspects

The paper is devoted to study the frequency shift in the solution of the generalized telegraph equation with a moving point-wise harmonic source. This equation contains the nonlocality in time derivatives which is expressed by the memory functions η(t) and γ(t), where η(t) smears the second time-derivative and γ(t) the first one. Moreover, in the Laplace domain we have ηˆ(s)=γˆ2(s). The generalized telegraph equation with an external source is solved by using the integral decomposition which allows us to write this solution as a product of the solution of the telegrapher equation with harmonic source and fγˆ(ξ,t) which is a function of the Laplace transform of memory function γ. Such obtained solution manifests the frequency shift which is illustrated in three examples of the memory functions γ(t): the localized case, its mixture with power-law, and the power-law case only. We show that only the first two cases have the wave front and the Doppler-like shift. The third example, despite the lack of wave fronts, also manifests the frequency shift. Thus it turns out that the frequency shift occurs regardless of the existence of a wave front, but it is more visible when such a front exists.

Contemporary Advancements in Education for Sustainable Development: A Qualitative Outlook

Education plays a pivotal role in advancing sustainability on a global scale. It serves as a crucial vehicle, offering individuals the understanding, means, and benefits necessary for achieving sustainable development. Sustainable development, at its core, seeks to meet present needs without compromising the ability of future generations to fulfill their specific requirements. This approach integrates economic, social, and environmental considerations, forming a shared foundation for all. Education for sustainability harnesses the entire educational system to equip students with the knowledge and skills needed to catalyze societal transformation toward a sustainable future. An integral aspect of sustainable development involves recognizing and respecting the positive heritage and legacy bestowed by past generations. Education for Sustainable Development (ESD) embodies a dynamic concept that envisions a new educational paradigm balancing human and economic well-being with cultural traditions and a profound regard for the Earth’s natural resources. ESD emphasizes the significance of learning in fostering a transition toward sustainability. It encompasses a range of educational facets, including citizenship education, the cultivation of a culture of peace, gender equality, respect for human rights, health education, population education, and the prudent management of natural resources. The transformation of education into a constructive tool is crucial for instilling awareness among students and global citizens alike. ESD employs transdisciplinary educational systems to cultivate ideas for continual learning, instill respect for human needs harmonized with sustainable resource use, and foster an awareness of global solidarity. By encouraging individuals to make decisions that shape the long-term future of the economy, ecology, and social welfare, ESD emerges as a practice of learning how to maintain equilibrium between humans and nature. In essence, education for sustainable development provides a pathway to harmonize the delicate balance between humanity and the environment, contributing to a future where both can thrive in tandem. Keywords: Education, Sustainability, Education for Sustainable Development, Transformation, Transition, Awareness, Gender Equality, Social Welfare, Environment