Background: The socio-clinical characteristics have been considered an important variable associated with COVID-19 and a predictor of morbidity and mortality. Convalescent plasma therapy (CPT) was one of the modalities used worldwide for COVID-19 treatment. In Iraq, there is a paucity of studies evaluating the socio-clinical variables of patients with severe COVID-19 treated with CPT. Objectives: This study aims to describe the socio-clinical characteristics of patients with severe COVID-19 treated with and without CPT in one of the main COVID-19 treatment centers in Iraq. Materials and Methods: A descriptive cross-sectional study was conducted between May 15 and August 14, 2020, at the main COVID-19 treatment center in Anbar Governorate, west of Iraq. Out of 529 hospitalized patients, a total of 438 with severe disease were enrolled in the study. Results: The participants’ mean age was 49.9±13.8 years. The majority of the subjects were males, aged ≥40 years, residing in urban areas. 65.2% of the patients had at least one comorbidity, and 6.4% were smokers. Hypertension and diabetes mellitus represented the two commonest comorbid conditions. All patients have required oxygen therapy; 41.1% were performed with continuous positive airway pressure. Male patients aged ≥60, and patients with comorbidities received CPT at a higher frequency. Conclusion: This study corroborates the findings from other studies that certain socio-clinical characteristics had an association with hospitalization related to severe COVID-19. Convalescent plasma was administered in more than one-fifth of the COVID-19 hospitalized patients in Anbar during the early pandemic phase.
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