The first focus of this study is to investigate the design and behavior of locally built solar dryer during processing henna leaves. This was performed through the determination of the most important parameters that effect drying process. Appropriately, it was found that solar radiation has a direct effect on the collector outlet air temperature and consequently the product moisture content. Accordingly, high radiations lead having high air temperature at the drying chamber and consequently, the moisture content will decrease rapidly. Similarly, lower radiations will still lead to decrease of the moisture content, however, the drying rate will be less important than at high radiations. On the other hand, air velocity has an inverse dissipative effect of the energy and its increase leads to the decrease of the outlet temperature of the solar collector. Indeed, the highest outlet temperature from the solar collector was around 32 °C at an air velocity of 2 m/s. At 5.5 m/s, this temperature dropped to around 27 °C. The second objective of this study is to present the effect of different drying methods (i.e. forced convective solar drying and open sun drying) of Lawsonia inermis on the content of secondary metabolites (phenolic and flavonoid compounds) and compare the results with fresh henna samples. The yield of phenolic compounds was determined, and the dry crude extracts were found to be richer than the fresh sample in all of the drying modes used. The best yields are obtained with convective solar dryer and open sun drying samples (28.6 and 13.93%), respectively. The total phenolic and flavonoid contents of convective solar dryer product were 25 and 10% higher than open sun dried samples. Antioxidant tests (DPPH, ABTS, and ferric reducing power) revealed the scavenging and reducing abilities of the extract dried with the solar dryer. The values of antioxidant capacities measured by the three different methods were all consistent, appropriate, and highly correlative for assessing total antioxidant capacities. The solar dryer allows the preservation or even the increase of the antioxidant activity of the tested extracts.