Air Change Research Articles

A theoretical and numerical analysis of solar chimney in multi-storey atrium building

Current research efforts on solar chimney are much on those configurations with single space or single vent, hampering its applications in complex buildings. To expand its implementation, the viability of solar chimney in multi-storey atrium buildings was explored numerically and theoretically. It was known that its natural ventilation performance can fulfil the WHO requirements (i.e., 6 air change per hour, ACH) even under low solar radiation of 200 W/m2 if it is appropriately designed, such as cavity gap (d), cavity height (Hc), solar radiation (Q), and window width (W). Its natural ventilation rate was found to be positively linear to the exponential form of the analyzed factors in this study, including cavity gap (d0.63∼0.69), cavity height (Hc0.59∼0.60), solar radiation (Q0.42∼0.43), and window width (W0.14∼0.20). The impacts of cavity gap and solar radiation are relatively weaker for big space such as atrium than those scenarios with single-space ventilation in the literature. The volume of the connected space was found to affect its natural ventilation performance, where the obtained ventilation rate of 4-storey is averagely 5.1 % lower than those of 3-storey buildings. A theoretical model was developed and experimentally validated, for the first time, to predict the natural ventilation rate of solar chimney when it is applied to the atrium with multiple air inlets. It was also noticed that the same theoretical model can be applied to the atrium buildings with odd and even storeys, but the area coefficients are different. The research outcomes of this study confirm the viability of solar chimney in complex buildings and offer a theoretical foundation for its implementation.

Placental DNA methylation signatures of prenatal air pollution exposure and potential effects on birth outcomes: an analysis of three prospective cohorts.

Pregnancy air pollution exposure (PAPE) has been linked to a wide range of adverse birth and childhood outcomes, but there is a paucity of data on its influence on the placental epigenome, which can regulate the programming of physiological functions and affect child development. This study aimed to investigate the association between prenatal air pollutant exposure concentrations and changes in placental DNA methylation patterns, and to explore the potential windows of susceptibility and sex-specific alterations. This multi-site study used three prospective population-based mother-child cohorts: EDEN, PELAGIE, and SEPAGES, originating from four French geographical regions (Nancy, Poitiers, Brittany, and Grenoble). Pregnant women were included between 2003 and 2006 for EDEN and PELAGIE, and between 2014 and 2017 for SEPAGES. The main eligibility criteria were: being older than 18 years, having a singleton pregnancy, and living and planning to deliver in one of the maternity clinics in one of the study areas. A total of 1539 mother-child pairs were analysed, measuring placental DNA methylation using Illumina BeadChips. We used validated spatiotemporally resolved models to estimate PM2·5, PM10, and NO2 exposure over each trimester of pregnancy at the maternal residential address. We conducted a pooled adjusted epigenome-wide association study to identify differentially methylated 5'-C-phosphate-G-3' (CpG) sites and regions (assessed using the Infinium HumanMethylationEPIC BeadChip array, n=871), including sex-specific and sex-linked alterations, and independently validated our results (assessed using the Infinium HumanMethylation450 BeadChip array, n=668). We identified four CpGs and 28 regions associated with PAPE in the total population, 469 CpGs and 87 regions in male infants, and 150 CpGs and 66 regions in female infants. We validated 35% of the CpGs available. More than 30% of the identified CpGs were related to one (or more) birth outcome and most significant alterations were enriched for neural development, immunity, and metabolism related genes. The 28 regions identified for both sexes overlapped with imprinted genes (four genes), and were associated with neurodevelopment (nine genes), immune system (seven genes), and metabolism (five genes). Most associations were observed for the third trimester for female infants (134 of 150 CpGs), and throughout pregnancy (281 of 469 CpGs) and the first trimester (237 of 469 CpGs) for male infants. These findings highlight the molecular pathways through which PAPE might affect child health in a widespread and sex-specific manner, identifying the genes involved in the major physiological functions of a developing child. Further studies are needed to elucidate whether these epigenetic changes persist and affect health later in life. French Agency for National Research, Fondation pour la Recherche Médicale, Fondation de France, and the Plan Cancer.

Noise as an Extrinsic Variable in the Animal Research Facility.

Animal research facilities are noisy environments. The high air change rates required in animal housing spaces tend to create higher noise levels from the heating and cooling systems. Housing rooms are typically constructed of hard wall material that is easily cleaned but simultaneously highly reverberant, meaning that the sound cannot be controlled/attenuated so the sounds that are generated bounce around the room uncontrolled. (Soft, sound-absorbing surfaces generally cannot be used in animal facilities because they collect microbes; various wall surface features and sound control panel options are available, although rarely used.) In addition, many of our husbandry tasks such as cage changing, animal health checks, cleaning, and transporting animals produce high levels of noise. Finally, much of the equipment we have increasingly employed in animal housing spaces, such as ventilated caging motors, biosafety, or procedure cabinets, can generate high levels of background noise, including ultrasound. These and many additional factors conspire to create an acoustic environment that is neither naturalistic nor conducive to a stress-free environment. The acoustic variability both within and between institutions can serve as an enormous confounder for research studies and a threat to our ability to reproduce studies over time and between research laboratories. By gaining a better appreciation for the acoustic variables, paired with transparency in reporting the levels, we might be able to gain a better understanding of their impacts and thereby gain some level of control over such acoustic variables in the animal housing space. The result of this could improve both animal welfare and study reproducibility, helping to address our 3Rs goals of Replacement, Reduction, and Refinement in the animal biomedical research enterprise.

Utilizing periodic boundary conditions to save computational resources for assessing building natural ventilation in urban areas

For the first time in literature, we innovatively conducted CFD simulations with periodic boundary conditions to predict coupled indoor-outdoor airflows for a full-scale 3D six-floor residential building unit in urban areas with uniformly building clusters. A few influencing parameters on building ventilation performance are comprehensively analyzed, including the impacts of the surrounding buildings, wind incident angle (θ), external opening designs, cross or single-sided ventilation modes, and indoor facilities. Ventilation evaluation is contingent on factors including air change rate per hour (ACH), the corresponding ACH of purging flow rate (ACHPFR), and age of air (τ).Results show that the efficiency of natural ventilation on each floor differs from previous research conclusions after considering the impacts of surrounding buildings. Single-sided ventilation is significantly less effective than cross-ventilation in all scenarios. Most cross-ventilation cases have one-order greater ACH and ACHPFR values compared to those with single-sided ventilation. The window-to-wall ratio on the windward and leeward sides can affect the natural ventilation rate of the corresponding rooms. A large leeward opening helps to increase the ventilation rate, especially for the rooms on the upper floor, but it decreases the ventilation for the rooms near the ground. Indoor furniture has an insignificant impact on outdoor airflow and natural ventilation efficiency.

Study of air deionization factors

The object of research is the dynamics in the concentration of air ions and suspended particles in atmospheric air and in supply-exhaust ventilation systems. An urgent task is to determine the factors and obtain quantitative data on the deionization of the atmospheric air that enters the environment where people live. Quantitative data on changes in the concentration of air ions depending on the time of day, temperature, and relative air humidity have been established. It was shown that even in the absence of significant man-made influence on the concentration of suspended particles, this indicator is at least 7000 cm-3. In the presence of wind, this indicator reaches 30000 cm-3 and higher. Measurement of the spectrum of suspended particles in the range of 0,3–6,0 μm showed that the predominant fraction is particles with sizes of about 3 μm. Studies have been conducted on changes in the concentrations of air ions in supply-exhaust ventilation systems. It was established that in the air duct made of galvanized iron, which has a length of 16 m, the concentration of negative air ions is reduced by 67 %, and positive by 78 %. Laboratory studies of air deionization in air ducts made of different materials were carried out. There is significant air deionization in metal and cardboard ducts while it is absent in wooden ducts. This indicates the electrical nature of deionization. A calculation method for forecasting the aero-ionic mode of premises, taking into account the factors of air deionization, is proposed. For rooms with supply-exhaust ventilation, a calculation apparatus is proposed taking into account the air exchange rate (the number of complete air changes per unit of time). The results make it possible to choose the required performance of artificial air ionization devices for normalizing the aero-ionic regimes in the premises

Comparison of infiltration of different particle sizes and influencing parameters

The size fractional distribution of indoor and outdoor particles was investigated to understand how particle size, air change rate, building airtightness, and meteorological parameters affect particle infiltration behavior. The experiments were performed for two apartments, one without airtightness intervention and the other after sealing the window gaps. Although the correlation analysis showed that the indoor PM trend was highly dependent on outdoor conditions, different penetration behavior for different particle sizes was noticed. Despite the absence of indoor sources, the size fractional distribution of particles in the indoor and outdoor environment did not follow the same pattern. Moreover, airtightness somehow reduced the envelope effective leakage area and slightly decreased the indoor/outdoor ratio and infiltration factor for all particle sizes; however, it did not affect the relative infiltrability. The highest penetration rates were observed in the size range of 0.3–1.0 μm and the lowest rates were in the 2.5–10 μm range. Although with particles greater than 0.3 μm, the infiltration of fine particles was higher than that of coarse particles, the infiltrability of PM < 0.3 was slightly lower than PM0.3-1.0, probably due to the penetration dominated by the concentration gradient. Particle size, envelope airtightness, and outdoor source were the main factors that governed fractional particle infiltration, overshadowing the effect of meteorological parameters. Furthermore, window airtightness decreased the indoor-outdoor PM correlation, especially for coarser particles. It caused approximately a 1-h lag-time between the indoor and outdoor PM trend, a positive point in case of accidental increase of outdoor levels.

Thermal insulation box design for maintaining cool temperature and the postharvest quality of okra

Postharvest loss of okra is caused by its high respiration rate and temperature fluctuations in the supply chain. To address this, five thermal insulation boxes were designed, combining different materials, and evaluated for okra quality during simulated transportation and storage. The treatments included the standard foam box, metalized foam sheet (two layers consisting of aluminum foil and expanded polyethylene), prototype-A (three layers consisting of dual layer of aluminum foil and expanded polyethylene), prototype-B (four layers consisting of aluminum foil, nonwoven, expanded polyethylene, and aluminum foil), and standard regular slotted container. Material tests revealed that aluminum foil and expanded polyethylene had the lowest thermal heat energy. The composite sandwich box design, prototype-A, demonstrated the highest maximum insulation time of 28 h and thermal resistance of 0.332 m2°C/W. Prototype-A and prototype-B effectively maintained low temperature fluctuation, minimized air and okra temperature changes, and maintained 6.19 to 8.25 % CO2, which was within an acceptable range of 4–10 % for okra. Both prototypes exhibited reduced percentage mass loss in okra below 5 %. Importantly, both prototypes demonstrated the lowest incidence of okra pod surface browning and maintained the quality for 6 d, surpassing metalized foam sheet and standard regular slotted container. These findings offer sandwich design with 3 or 4 layers as promising alternatives for thermal insulation boxes in cold chain management, enhancing the transport packaging of okra under ambient environments compared to the standard foam box.

Bedroom Concentrations and Emissions of Volatile Organic Compounds during Sleep.

Because humans spend about one-third of their time asleep in their bedrooms and are themselves emission sources of volatile organic compounds (VOCs), it is important to specifically characterize the composition of the bedroom air that they experience during sleep. This work uses real-time indoor and outdoor measurements of volatile organic compounds (VOCs) to examine concentration enhancements in bedroom air during sleep and to calculate VOC emission rates associated with sleeping occupants. Gaseous VOCs were measured with proton-transfer reaction time-of-flight mass spectrometry during a multiweek residential monitoring campaign under normal occupancy conditions. Results indicate high emissions of nearly 100 VOCs and other species in the bedroom during sleeping periods as compared to the levels in other rooms of the same residence. Air change rates for the bedroom and, correspondingly, emission rates of sleeping-associated VOCs were determined for two bounding conditions: (1) air exchange between the bedroom and outdoors only and (2) air exchange between the bedroom and other indoor spaces only (as represented by measurements in the kitchen). VOCs from skin oil oxidation and personal care products were present, revealing that many emission pathways can be important occupant-associated emission factors affecting bedroom air composition in addition to direct emissions from building materials and furnishings.

Nanopore arrays with TMOKE-enhanced high performance sensing

Magneto-plasmon sensing structure based on surface plasmon resonance (SPR) and magneto-optical (MO) effect has become a hot research topic in recent years. In this work, we propose a magneto-plasmon crystal consisting of an Au/Co double-layer nanoporous structure with optically thick Au film as a substrate. Due to the excitation of high-quality SPR, a Fano-like transverse magneto-optical Kerr (TMOKE) spectrum with subnanometer bandwidth is realized. A sensitivity of up to 677 nm RIU−1 is detected under subtle refractive index changes in air, and all the calculated figure of merits (FOM) are higher than 104 RIU−1. In addition, in order to highlight the superiority of the sensing performance of the MO plasmon (MOSPR) sensor, we compare the MOSPR sensor with the SPR sensor and calculate their FOM in different refractive index environments. The results show that the FOM of the MOSPR sensor is two orders of magnitude higher than that of the SPR sensor, which proves that the performance of the MOSPR sensor is significantly better than that of the SPR sensor and provides a theoretical basis for biosensing and gas detection based on magneto plasmon.

Performance investigation of a novel positively or negatively pressurized operating room for infection control

Operating rooms are often positively pressurized and maintained at a higher pressure than adjacent areas, preventing contaminated air from entering the sterile surgical environment. However, the COVID-19 outbreak has necessitated the construction of negatively pressurized operating rooms for contagious patients, preventing contaminated air from escaping into adjacent spaces. Therefore, this study developed a heating, ventilation, and air-conditioning (HVAC) system that can have a dual function pressurization, positively or negatively pressurized. High-efficiency particulate air (HEPA) filters were used for filtration. Then, a variable-speed driven (VSD) HVAC system modulates the pressure in response to environmental conditions when changing the pressure from positive to negative or while the door opens. At the same time, the air change rate (ACR) for dilution was implemented through the separated HVAC systems control schemes. Field measurements were performed to validate the results of a computational fluid dynamics (CFD) simulation, which was conducted to compare air particle distributions in a positively and negatively pressurized operating room and the effects of air curtains. The results showed that the positive pressurized operating room has a better airflow pattern and dilutes contaminants faster. In contrast, the negative pressurized system is the best solution for reducing the chance of airborne infection, particularly for contagious patients. Furthermore, utilizing air curtains can provide a better barrier against airborne contaminants, increasing the efficiency of contaminant control measures. The ventilation efficiency could be increased by approximately 10 % by applying an air curtain with a velocity of 0.5 m/s under both types of pressurization.

Improvement of Temperature Measurement Accuracy of Hot Airflow Using Ultrafine Thermo-Sensitive Fluorescent Wires of Lumisis Phosphor.

In this study, the fluorescence properties of Lumisis, a phosphor that can be easily applied to ultrafine wires, were evaluated. By evaluating the wavelength characteristics of Lumisis phosphor, we investigated the possibility of applying it to a dual-wavelength laser-induced fluorescence (LIF) measurement system and evaluated the accuracy of temperature measurements. The difference between the decrease in the percentage intensities of the red and green fluorescence of Lumisis phosphors showed that two-color LIF was possible. The Lumisis phosphor-mixture ratio was optimized as 1:1.25, and the average measurement error of the fluorescent wire was 0.20 K, as evaluated through uncertainty analysis. Finally, the application of this measurement method to hot air jet phenomena showed that this method accurately captures the temperature changes in hot air, thus proving its validity.

The prevalence and association of measured and perceived indoor air quality, housing characteristics, and residents’ behavior and health

BackgroundIn social housing buildings, poor indoor air quality (IAQ) has been shown to be more prevalent, and residents living in social housing areas are often more vulnerable and susceptible to adverse health effects from IAQ.AimTo examine the state and the association of measured and perceived IAQ, how housing characteristics and residents' behavior are associated with IAQ, and the association with residents' health.MethodThe HOME-Health study is a cross-sectional study among residents living in social housing in Denmark (n = 432). Seasonal measurements examined the IAQ by a 14-day period measuring carbon dioxide (CO2), temperature (TP), relative humidity (RH), and air change rate. Residents' self-reported behavior, comfort, and health were obtained from a structured interview.ResultsThermal discomfort and draught were the most common challenges. During summer, the mean TP was higher, the mean RH was lower, and residents more frequently reported dry air in homes where it was not possible to create cross ventilation. There were a higher mean CO2 and RH when crowdedness increased, particularly during winter. In addition, the proportion of residents reporting dry air was higher when CO2-level was below 1,000 ppm. When the mean RH-level was above 50%, a higher proportion of residents reported experiencing damp air, and when the mean RH-level was below 40% residents more frequently reported dry air. Perception of bad air quality was higher when the mean CO2-level exceeded 1,000 ppm. Additionally, residents reported being most thermally comfortable when the TP was within the range of 20–20.99°C and least comfortable within a range of 22–22.99°C. The residents' perceived experience of impaired IAQ was associated with negative general health symptoms.ConclusionIt is key that homes have the capability to create cross ventilation in order to allow for proper ventilation and to avoid overheating. When evaluating IAQ it is important to not only consider the measured parameters but to also include the residents' behavior and perception of IAQ as these both are related to the actual IAQ and associated health effects.

Association of ambient air pollution with hemoglobin levels and anemia in the general population of Korean adults

BackgroundEmerging evidence has suggested significant associations between ambient air pollution and changes in hemoglobin levels or anemia in specific vulnerable groups, but few studies have assessed this relationship in the general population. This study aimed to evaluate the association between long-term exposure to air pollution and hemoglobin concentrations or anemia in general adults in South Korea.MethodsA total of 69,830 Korean adults from a large-scale nationwide survey were selected for our final analysis. Air pollutants included particulate matter with an aerodynamic diameter less than or equal to 10 micrometers (PM10), particulate matter with an aerodynamic diameter less than or equal to 2.5 micrometers, nitrogen dioxide, sulfur dioxide (SO2), and carbon monoxide (CO). We measured the serum hemoglobin concentration to assess anemia for each participant.ResultsIn the fully adjusted model, exposure levels to PM10, SO2, and CO for one and two years were significantly associated with decreased hemoglobin concentrations (all p < 0.05), with effects ranging from 0.15 to 0.62% per increase in interquartile range (IQR) for each air pollutant. We also showed a significant association of annual exposure to PM10 with anemia (p = 0.0426); the odds ratio (OR) [95% confidence interval (CI)] for anemia per each increase in IQR in PM10 was estimated to be 1.039 (1.001–1.079). This association was also found in the 2-year duration of exposure (OR = 1.046; 95% CI = 1.009–1.083; adjusted Model 2). In addition, CO exposure during two years was closely related to anemia (OR = 1.046; 95% CI = 1.004–1.091; adjusted Model 2).ConclusionsThis study provides the first evidence that long-term exposure to air pollution, especially PM10, is significantly associated with reduced hemoglobin levels and anemia in the general adult population.

Theoretical analysis and numerical study of natural convection inside combined solar chimney

AbstractSolar chimneys may induce natural ventilation through solar radiation. However, sufficient theoretical studies are needed as a basis to fully exploit passive design in practical green building design. In this work, we investigate the heat transfer properties of turbulent natural convective flows in a combined solar chimney with a thermal flux at the absorption wall by means of theoretical analysis and numerical simulations. Two different flow patterns have been found, one with a clear thermal boundary layer flow pattern and the other without, based on high Rayleigh numbers. For flow development in these two flow regimes, the transient scaling analysis is performed separately and the control mechanism for each phase is presented. Some new scale relationships are established to characterize the ventilation performance of solar chimneys, including thermal boundary layer thickness δT, velocity vT, mass flow m, and so on. For the distinct thermal boundary layers, δT,s ~ HΓ2/5/Bo1/5κ2/5, vT,s ~ Bo2/5κ4/5Γ1/5/H, m ~ ρBo1/5κ2/5Γ3/5. For nonobvious thermal boundary layers, vT,f ~ Bo1/3κ/H2/3W1/3, m ~ ρBo1/3κ/A2/3. The important scale relationships are validated using corresponding numerical simulation data, such as the mass flow rate scale M ~ (Γ/κ)3/5Bo1/5 in the distinct thermal boundary layer flow state, and so on. The air changes per hour and heat exchange efficiencies are calculated for a solar chimney with a fixed height‐to‐width ratio to provide a basis for the design of a solar chimney.

Ventilation during COVID-19 in a school for students with intellectual and developmental disabilities (IDD).

This study examined the correlation of classroom ventilation (air exchanges per hour (ACH)) and exposure to CO2 ≥1,000 ppm with the incidence of SARS-CoV-2 over a 20-month period in a specialized school for students with intellectual and developmental disabilities (IDD). These students were at a higher risk of respiratory infection from SARS-CoV-2 due to challenges in tolerating mitigation measures (e.g. masking). One in-school measure proposed to help mitigate the risk of SARS-CoV-2 infection in schools is increased ventilation. We established a community-engaged research partnership between the University of Rochester and the Mary Cariola Center school for students with IDD. Ambient CO2 levels were measured in 100 school rooms, and air changes per hour (ACH) were calculated. The number of SARS-CoV-2 cases for each room was collected over 20 months. 97% of rooms had an estimated ACH ≤4.0, with 7% having CO2 levels ≥2,000 ppm for up to 3 hours per school day. A statistically significant correlation was found between the time that a room had CO2 levels ≥1,000 ppm and SARS-CoV-2 PCR tests normalized to room occupancy, accounting for 43% of the variance. No statistically significant correlation was found for room ACH and per-room SARS-CoV-2 cases. Rooms with ventilation systems using MERV-13 filters had lower SARS-CoV-2-positive PCR counts. These findings led to ongoing efforts to upgrade the ventilation systems in this community-engaged research project. There was a statistically significant correlation between the total time of room CO2 concentrations ≥1,000 and SARS-CoV-2 cases in an IDD school. Merv-13 filters appear to decrease the incidence of SARS-CoV-2 infection. This research partnership identified areas for improving in-school ventilation.

Pentagon Found Daily, Metagenomic Detection of Novel Bioaerosol Threats to Be Cost-Prohibitive: Can Virtualization and AI Make It Cost-Effective?

In 2022, the Pentagon Force Protection Agency found threat agnostic detection of novel bioaerosol threats to be "not feasible for daily operations" due to the cost of reagents used for metagenomics, cost of sequencing instruments, and cost of labor for subject matter experts to analyze bioinformatics. Similar operational difficulties might extend to many of the 280,000 buildings (totaling 2.3 billion square feet) at 5,000 secure US Department of Defense military sites, 250 Navy ships, as well as many civilian buildings. These economic barriers can still be addressed in a threat agnostic manner by dynamically pooling samples from dry filter units, called spike-triggered virtualization, whereby pooling and sequencing depth are automatically modulated based on novel biothreats in the sequencing output. By running at a high average pooling factor, the daily and annual cost per dry filter unit can be reduced by 10 to 100 times depending on the chosen trigger thresholds. Artificial intelligence can further enhance the sensitivity of spike-triggered virtualization. The risk of infection during the 12- to 24-hour window between a bioaerosol incident and its detection remains, but in some cases it can be reduced by 80% or more with high-speed indoor air cleaning exceeding 12 air changes per hour, which is similar to the rate of air cleaning in passenger airplanes in flight. That level of air changes per hour or higher is likely to be cost-prohibitive using central heating ventilation and air conditioning systems, but it can be achieved economically by using portable air filtration in rooms with typical ceiling heights (less than 10 feet) for a cost of approximately $0.50 to $1 per square foot for do-it-yourself units and $2 to $5 per square foot for high-efficiency particulate air filters.

Long-term outcomes following pediatric endoscopic titanium ossiculoplasty: A single-institution experience

IntroductionEndoscopic ossicular chain reconstruction (OCR) in adults has demonstrated equivalent outcomes to the traditional microscopic approach. Less data exist on endoscopic OCR outcomes in children, who have unique considerations including a smaller transcanal corridor and variable pathology. The purpose of this study was to investigate surgical and audiometric outcomes in children undergoing fully endoscopic and endoscopic-assisted OCR in both the short and long-term. MethodsRetrospective review of all children (<17 years) who underwent endoscopic OCR at one tertiary care center between 2017 and 2021. Children undergoing primary and revision endoscopic OCR with either partial (PORP) and total ossicular reconstruction prostheses (TORP) were included. Children undergoing surgery for juvenile otosclerosis or congenital stapes fixation, or any child receiving a stapes prosthesis were excluded. Primary outcome measures were post-operative change in 4 frequency (500 Hz, 1, 2, 4 KHz) air conduction pure tone average (AC PTA) and change in air-bone gap (ABG). Secondary measures included need for readmission and/or revision surgery, complication rate, and surgery duration. ResultsSeventeen patients met inclusion criteria. Average age was 11.3 years (range, 5–17 years); 14 were male. A variety of fixed length, titanium total and partial prostheses were used. The most common prosthesis length was 2 mm (range 2–5 mm), and there were no intra- or perioperative complications. Mean long-term follow-up was 2.6 years. Most common pathology was congenital cholesteatoma (11/17, 64%), followed by chronic otitis media with tympanic membrane perforation (5/17, 29.4%), and extruded prosthesis (1/17, 5.9%). Intraoperatively, the most common finding was incus erosion (10/17, 58.8%), followed by malleus erosion (6/17, 35.3%), stapes erosion (4/17, 23.5%), and stapes absence (4/17, 23.5%). Eight children (47%) were reconstructed with PORPs, and 9 children (52.9%) were reconstructed with TORPs. Average ABG improved from 36.8 dB preoperatively to 19.9 dB postoperatively in the short-term and remained stable at 19.5 dB in the long-term. Average short-term ABG improvement was 4.2 dB for PORPs and 18 dB for TORPs. In the long-term, average ABG improved by 2.3 dB in PORPs and 13.4 dB in TORPs. PORPs had higher rates of ABG closure and lower AC PTAs than TORPs in the long-term. DiscussionEndoscopic ossiculoplasty is a viable option in children presenting with ossicular erosion from various causes. Audiometric improvement following endoscopic partial and total ossicular reconstruction remains stable over time, with a preference towards partial in the long-term, and mirrors published outcomes for microscopic surgery.

A GPU-accelerated computational fluid dynamics solver for assessing shear-driven indoor airflow and virus transmission by scale-resolved simulations

We explore the applicability of MATLAB for 3D computational fluid dynamics (CFD) of shear-driven indoor airflows. A new scale-resolving, large-eddy simulation (LES) solver titled DNSLABIB is proposed for MATLAB utilizing graphics processing units (GPUs). In DNSLABIB, the finite difference method is applied for the convection and diffusion terms while a Poisson equation solver based on the fast Fourier transform (FFT) is employed for the pressure. The immersed boundary method (IBM) for Cartesian grids is proposed to model solid walls and objects, doorways, and air ducts by binary masking of the solid/fluid domains. The solver is validated in two canonical reference cases and against experimental data. Then, we demonstrate the validity of DNSLABIB in a room geometry by comparing the results against another CFD software (OpenFOAM). Next, we demonstrate the solver performance in several isothermal indoor ventilation configurations and the implications of the results are discussed in the context of airborne transmission of COVID-19. The novel numerical findings using the new CFD solver are as follows. First, a linear scaling of DNSLABIB is demonstrated and a speed-up by a factor of 3-4 is also noted in comparison to similar OpenFOAM simulations. Second, ventilation in three different indoor geometries are studied at both low (0.1 m/s) and high (1 m/s) airflow rates corresponding to Re=5000 and Re=50000. An analysis of the indoor CO2 concentration is carried out as the room is emptied from stale, high CO2 content air. We estimate the air changes per hour (ACH) values for three different room geometries and show that the numerical estimates from 3D CFD simulations differ by 80%–150% (Re=50000) and 75%–140% (Re=5000) from the theoretical ACH value based on the perfect mixing assumption. Third, the analysis of the CO2 probability distributions (PDFs) indicates a relatively non-uniform distribution of fresh air indoors. Fourth, utilizing a time-dependent Wells-Riley analysis, an example is provided on the growth of the cumulative infection risk which is shown to reduce rapidly after the ventilation is started. The average infection risk is shown to reduce by a factor of 2 for lower ventilation rates (ACH=3.4-6.3) and 10 for the higher ventilation rates (ACH=37-64). Finally, we utilize the new solver to comment on respiratory particle transport indoors. A key contribution of the paper is to provide an efficient, GPU compatible CFD solver environment enabling scale-resolved simulations (LES/DNS) of airflow in large indoor geometries on a single GPU designed for high-performance computing. The demonstrated efficacy of MATLAB for GPU computing indicates a high potential of DNSLABIB for various future developments on airflow prediction.

Influence of air changes per hour on hydrogen leaks in mechanically ventilated enclosures

The integration of hydrogen energy systems into nearly zero-emission buildings (nZEB) is emerging as a viable strategy to curtail greenhouse gas emissions associated with energy use in these buildings. However, the indoor or outdoor placement of certain hydrogen system components or equipment necessitates stringent safety measures, particularly in confined environments. This study aims to investigate the dynamics of hydrogen dispersion within an enclosure featuring forced ventilation, analyzing the interplay between leakage flow rates and ventilation efficiency both experimentally and numerically. To simulate hydrogen's behavior, helium gas, which shares similar physical characteristics with hydrogen, was utilized in experiments conducted at leakage flows of 4, 8, and 10 L/min, alongside a ventilation rate of 30 air changes per hour (ACH). The experiments revealed that, irrespective of the leakage rate, the oxygen concentration returned to its initial level approximately 11 min post-leakage at a ventilation rate of 30 ACH. This study also encompasses a numerical analysis to validate the experimental findings and assess the congruence between helium and hydrogen behaviors. Additionally, the impact of varying ACH rates (30, 45, 60, 75) on the concentrations of oxygen and hydrogen was quantified through numerical analysis for different hydrogen leakage rates (4, 8, 10, 20 L/min). The insights derived from this research offer valuable guidance for building facility engineers on designing ventilation systems that ensure hydrogen and oxygen concentrations remain within safe limits in hydrogen-utilizing indoor environments.

Investigation of Hydrogen-Blended Natural Gas Pipelines in Utility Tunnel Leakage and Development of an Accident Ventilation Strategy for the Worst Leakage Conditions

The development of hydrogen-blended natural gas (HBNG) increases the risk of gas transportation and presents challenges for pipeline security in utility tunnels. The objective of this study is to investigate the diffusion properties of HBNG in utility tunnels and evaluate the effectiveness of various ventilation mechanisms. The numerical simulation software Fluent 2023 R1 is applied to simulate and analyze the leakage of small holes in a HBNG pipeline in the natural gas compartment. By examining the leaking behavior of HBNG through small holes in different circumstances, we aimed to identify the most unfavorable operational situation for leakage. Subsequently, we analyzed the ventilation strategy for sub-high-pressure pipes at various pressure levels in this unfavorable condition. This study’s findings demonstrate that blending hydrogen improves the gas diffusion capacity and increases the likelihood of explosion. The primary factors that influence the pattern of leakage are the size of the leaking holes and the pressure of the pipeline. The gas compartment experiences the most unfavorable working conditions for natural gas pipeline leaks when there are higher pressures, wider leak openings, higher hydrogen blending ratios (HBRs), and leaks in close proximity to an air inlet. When the HBR is 20%, the minimum accident ventilation rates for pressures of 0.4 MPa and 0.8 MPa are 15 air changes per hour and 21 air changes per hour, respectively. The maximum allowable wind speed for accident ventilation is 5 m/s, as regulated by China’s national standard, GB 50838-2015. This regulation makes it difficult to minimize the risk of leakage in a 1.6 MPa gas pipeline. It is recommended to install a safety interlock device to quickly shut off the pipeline in the event of a leak in order to facilitate the dispersion of the substance.