Adverse Environmental Effects Research Articles

Scanning the Horizon for Environmental Applications of Genetically Modified Viruses Reveals Challenges for Their Environmental Risk Assessment.

The release of novel genetically modified (GM) virus applications into the environment for agricultural, veterinary, and nature-conservation purposes poses a number of significant challenges for risk assessors and regulatory authorities. Continuous efforts to scan the horizon for emerging applications are needed to gain an overview of new GM virus applications. In addition, appropriate approaches for risk assessment and management have to be developed. These approaches need to address pertinent challenges, in particular with regard to the environmental release of GM virus applications with a high probability for transmission and spreading, including transboundary movements and a high potential to result in adverse environmental effects. However, the current preparedness at the EU and international level to assess such GM virus application is limited. This study addresses some of the challenges associated with the current situation, firstly, by conducting a horizon scan to identify emerging GM virus applications with relevance for the environment. Secondly, outstanding issues regarding the environmental risk assessment (ERA) of GM virus applications are identified based on an evaluation of case study examples. Specifically, the limited scientific information available for the ERA of some applications and the lack of detailed and appropriate guidance for ERA are discussed. Furthermore, considerations are provided for future work that is needed to establish adequate risk assessment and management approaches.

Less brodifacoum in baits results in greater accumulation in the liver of captive Rattus norvegicus in a no-choice trail

AbstractAnticoagulants are widely used as potent cumulative rodenticides; however, they are also associated with adverse environmental effects, such as intoxication of non-target animals. To ensure user safety, in the EU the use of anticoagulants containing active substances of > 30 ppm is restricted to professionals as these substances are toxic to reproduction Kat.1 A or B. Therefore, new products with < 30 ppm anticoagulant substance have been developed and registered. While the biological efficacy of these new products has been evaluated, the effect of their application on liver residues in targeted rodents was not examined before product introduction to the market. Our laboratory no-choice study on wild brown rats (Rattus norvegicus) showed that baits with high (50 ppm) and low (25 ppm) brodifacoum concentrations (with identical nontoxic cereal-based food components) presented 100% efficacy, although the 25 ppm bait exhibited significantly higher palatability and 4.5 times higher liver residues. Rats consumed 13.6 and 167.7 g of the 50 and 25 ppm baits, respectively, which corresponded to 3.16 and 14.91 μg/g of brodifacoum liver residues at their time of death. The experiments demonstrated that a decreased concentration of brodifacoum anticoagulant in rodenticide baits may lead to greater accumulation in rodent liver, thus indicating the urgent need to perform a detailed study of the environmental risks of low-concentration anticoagulant baits.

Recent Developments in Copper‐Based Catalysts for Enhanced Electrochemical CO2 Reduction

AbstractThe drastic climate change imposing adverse environmental effects receives serious research attention for finding a suitable solution. The replacement of conventional fossil energy sources with renewable and sustainable energy sources is the potential route; and thus, manifests as a viable solution. Accordingly, the electrocatalytic carbon dioxide (CO2) reduction process coupled with the renewable energy source is an emerging strategy for adopting a sustainable approach. However, the existing challenges in designing suitable catalyst, support material, electrolyte, inadequate selectivity, and intermediate reactions of CO2 reduction demand substantial research advancement. Numerous studies reported for the CO2 reduction process highlight the importance of catalyst design and product selectivity. Importantly, the copper‐based catalysts, capable in the output of multi‐carbon products, are reported as a “star” material. This review; therefore, focuses on catalyst design strategies, unique structural/morphological features, and product selectivity of diverse copper‐based catalysts. The outstanding findings of copper‐based catalysts and the corresponding products are critically discussed with adequate figures of merits. The impact of structural/morphological features on product selectivity is discussed in detail. The future scope and author perspectives on copper‐based catalysts for the feasible electrocatalytic CO2 reduction application are summarized.

Microalgae Inoculation Significantly Shapes the Structure, Alters the Assembly Process, and Enhances the Stability of Bacterial Communities in Shrimp-Rearing Water.

Intensive shrimp farming may lead to adverse environmental consequences due to discharged water effluent. Inoculation of microalgae can moderate the adverse effect of shrimp-farming water. However, how bacterial communities with different lifestyles (free-living (FL) and particle-attached (PA)) respond to microalgal inoculation is unclear. In the present study, we investigated the effects of two microalgae (Nannochloropsis oculata and Thalassiosira weissflogii) alone or in combination in regulating microbial communities in shrimp-farmed water and their potential applications. PERMANOVA revealed significant differences among treatments in terms of time and lifestyle. Community diversity analysis showed that PA bacteria responded more sensitively to different microalgal treatments than FL bacteria. Redundancy analysis (RDA) indicated that the bacterial community was majorly influenced by environmental factors, compared to microalgal direct influence. Moreover, the neutral model analysis and the average variation degree (AVD) index indicated that the addition of microalgae affected the bacterial community structure and stability during the stochastic process, and the PA bacterial community was the most stable with the addition of T. weissflogii. Therefore, the present study revealed the effects of microalgae and nutrient salts on bacterial communities in shrimp aquaculture water by adding microalgae to control the process of community change. This study is important for understanding the microbial community assembly and interpreting complex interactions among zoo-, phyto-, and bacterioplankton in shrimp aquaculture ecosystems. Additionally, these findings may contribute to the sustainable development of shrimp aquaculture and ecosystem conservation.

Transforming waste into sustainable building materials: Properties and environmental impacts of Geopolymer concrete with recycled concrete aggregates

<p>Industrial by-products such as cementitious materials or aggregates have the potential to mitigate the adverse environmental effects associated with traditional cement manufacture. Geopolymer Concrete (GPC) is more eco-friendly than conventional concrete because it does not require cement. GPC with Recycled concrete aggregates (RCA), Ground granulated blast furnace slag (GGBS), and Fly Ash (FA) reduce raw material use and create sustainable infrastructure. GPC compounds increase workability, slump value above standard concrete, and reduce the amount of water usage. The study examines GPC mechanical properties, durability, and environmental properties with different RCA content. The M30 concrete mix design is established by trial and error utilizing a 0.45 water/binder ratio. GPC with 0%, 10%, 20%, 30%, 40%, and 50% recycled coarse aggregate replaced natural aggregate(NA) by mass. GPC with 50% GGBS provides an early strength of 96% of normal compressive strength on day seven. The compressive, split tension, and flexural strengths exhibit significant improvement with up to a 40% substitution of NA with RA. These results highlight GPC's potential as a sustainable alternative in the construction sector.</p>

Physiological responses and removal mechanisms of ciprofloxacin in freshwater microalgae

Antibiotics, such as ciprofloxacin (CIP), are frequently detected in various environmental compartments, posing significant risks to ecosystems and human health. In this study, the physiological responses and elimination mechanisms of CIP in Chlorella sorokiniana and Scenedesmus dimorphus were determined. The exposure CIP had a minimal impact on the growth of microalgae, with maximum inhibit efficiency (IR) of 5.14% and 22.74 for C. sorokiniana and S. dimorphus, respectively. Notably, the photorespiration in S. dimorphus were enhanced. Both microalgae exhibited efficient CIP removal, predominantly through bioaccumulation and biodegradation processes. Intermediates involved in photolysis and biodegradation were analyzed through Liquid Chromatography High Resolution Mass Spectrometer (HPLC-MS/MS), providing insights into degradation pathways of CIP. Upregulation of key enzymes, such as dioxygenase, oxygenase and cytochrome P450, indicated their involvement in the biodegradation of CIP. These findings enhance our understanding of the physiological responses, removal mechanisms, and pathways of CIP in microalgae, facilitating the advancement of microalgae-based wastewater treatment approaches, particularly in antibiotic-contaminated environments.

Bioproducts from Waste Vegetable Oil: Perception and Engagement Study for Degreasers Based on Biocoal and Waste Coffee Grounds

Using waste vegetable oil for soap production represents a viable approach to prevent its detrimental release into water bodies and soil, thereby mitigating its adverse environmental effects. The artisanal soap-making process entails minimal investment and expertise, rendering it a straightforward procedure employing readily available inputs and equipment commonly found in everyday life. The principal objective of this study was to develop two bioproducts that address the environmental repercussions of improper disposal of waste vegetable oil, employing a perception and engagement survey of respondents. In conclusion, the derived products, synthesized from waste materials, effectively facilitated the removal of grease-based contaminants frequently encountered in workshops, automotive, and industrial settings, as well as in heavy cleaning applications, whether domestic or institutional.

Impact of a Broken Home Family on Children's Social Deviant Behavior

This research aims to examine the effects of broken families on children's social behavior. The methodology used for this research is based on literature review. Research results show, among other things, that the family plays an important role in the education and development of children's rights. However, when families are not functioning well, especially in broken families, it will have an impact on children. Children experience many emotions when they experience family breakdown, including: (1) being vulnerable and psychologically disturbed; (2) hate their parents; (3) is exposed too quickly to adverse environmental effects; (4) regard life as meaningless. ; (5) it is not easy to live with; and (6) having behavioral problems (7) Lack of self-esteem (8) The emergence of feelings of not paying attention to mental health (9) Showing hatred by destroying youth (10) Don't worry about yourself.

Innovative modification process of a natural gas power plant using self-sufficient waste heat recovery and flue gas utilization for a CCHP-methanol generation application: A comprehensive multi-variable feasibility study

Waste heat recovery holds significant importance in the context of natural gas power plants, as it facilitates the utilization of energy loss, leading to enhanced overall performance and mitigating adverse environmental effects. By harnessing and employing waste heat, power plants possess the capability to modify and optimize their operation, making a substantial contribution toward sustainable power/energy generation. Therefore, this study proposes a novel and eco-friendly approach to utilizing the flue gas emitted by a natural gas power plant. In addition to recovering waste heat, this method involves harnessing the flue gas for methanol production. The proposed system consists of an organic Rankine cycle, and absorption chiller, heating provider units, an electrolyzer for hydrogen generation, and a methanol synthesis unit. The novel method is implemented through computer-aided simulation using the Aspen HYSYS software and is subjected to an extensive analysis encompassing energy, exergy, environmental, and economic viewpoints. The simulation results exhibit producing 2712 kg/h of methanol with a purity of 99.97 mol%, 395.67 kg/s of hot water, 378 kg/s of chilled water, and 12253.57 kW of power. In this process, the energy and exergy efficiencies are 94.35% and 31.74%, respectively. Parametric study results demonstrate that reducing the gas turbine pressure and increasing the working fluid temperature in the evaporator of the absorption chiller cycle leads to improved exergy efficiency. Moreover, the multigeneration scenario shows a carbon dioxide footprint of 0.1564 kg/kWh and a total unit cost of product of 0.0485 $/GJ.

Investigating the Nexus Between Foreign Direct Investment and Sustainable Energy Transition: The Case of Vietnam

This study investigates how foreign direct investment (FDI) has impacted Vietnam’s sustainable energy transition from 1988 to 2020, utilising the autoregressive distributed lags (ARDL) technique for analysis. In the short term, a 1% increase in FDI is linked to a minor 0.015% reduction in the quality of energy transformation, indicating initial adverse environmental effects. However, in the long term, a notable improvement of 0.042% in energy transformation quality suggests that FDI-driven initiatives positively contribute to sustainable energy practices. Simultaneously, other factors such as the Consumer Price Index (CPI) demonstrate detrimental impacts both in the short term (0.039% decrease) and the long term (0.429% decrease), posing challenges to environmentally friendly projects. Conversely, the Green Economic Growth Index displays significant positive effects in both the short term (0.397% increase) and the long term (0.184% increase), emphasising the importance of fostering green economic growth. To accelerate the progress of sustainable energy transition, Vietnam is encouraged to implement policies encompassing the digitization of green initiatives, the introduction of green financing mechanisms, and the provision of supportive incentives for environmentally-conscious investors.

An ultrasensitive 4-aminophenol electrochemical sensors based on zinc and nitrogen-doped γ-cyclodextrin composites

4-Aminophenol (4-AP) is an environmental pollutant that is harmful to aquatic organisms and can cause long-term adverse effects in the aquatic environment. Herein, a Zn,N-γ-CD/GCE sensing platform was constructed by utilizing the complexation of Zn ions with γ-cyclodextrin (γ-CD), along with the composite of N-doped γ-cyclodextrin (N-γ-CD) and ZnCl2, for the detection of 4-AP. The presence of pore structures and hydrogen bonding groups in N-γ-CD enables effective capture of the target analyte through host–guest interactions, thereby enhancing the detection efficiency. The doping of Zn metal significantly improves the sensitivity of the sensing platform. After optimization, the detection limit of the Zn,N-γ-CD/GCE sensor was as low as 29.1 nM. Moreover, the sensor exhibits reliable repeatability, reproducibility, and stability. The practical feasibility of detecting 4-AP in real samples using this sensor demonstrated a recovery rate of 94.3 %–105.5 %, providing a new method for the accurate detection of 4-AP.

Assessment of the split tensile strength of fiber reinforced recycled aggregate concrete using interpretable approaches with graphical user interface

Incorporating recycled concrete aggregates into concrete represents a sustainable approach to mitigate the extraction of natural mineral resources and alleviate the adverse environmental effects associated with the concrete industry. Nevertheless, it encounters challenges due to the vulnerability of the hardened mortar adhering to natural aggregates. Thus, leading to an increased susceptibility to cracking and reduced strength. Therefore, this study utilized machine learning (ML) methods such as gene expression programming (GEP), random forest regression (RFR), artificial neural networks (ANN), ANN-Bagging, and ANN-Boosting models to forecast the split tensile strength (STS) of fiber-reinforced recycled aggregate concrete (FRRAC). To develop the models, 257 data points were gathered from experimental studies, encompassing ten influential input variables and considering the STS as the output variable. The accuracy of the models was assessed using statistical metrics. The five developed prediction models showcased excellent and reliable performance, with an impressive correlation coefficient (R) exceeding 0.80 during training and reaching 0.92 in testing. However, the GEP model outperformed the remaining four models, with an excellent R-value of 0.980 in training and 0.983 in testing. In addition, the standalone ANN model demonstrated performance on par with the ensemble ANN-Boosting model. In contrast, the ANN-Bagging ensemble model outperformed the individual ANN model, showcasing superior prediction accuracy with impressive R-values of 0.952 and 0.975 for training and testing, respectively. Moreover, the feature analysis based on SHapley Additive exPlanations (SHAP) revealed that fiber content, recycled aggregate density, cement, and water have the highest contribution in estimating the STS of FRRAC. Furthermore, a user-friendly graphical interface (GUI) has been developed to simplify the application of machine learning models in predicting the strength properties of concrete. In conclusion, the findings can encourage the utilization of FRRAC in both structural and non-structural reinforced concrete elements. Therefore, promoting the recycling and reuse of construction waste into building materials and thereby reducing environmental impact. Furthermore, incorporating recycled concrete aggregate in construction projects has the potential to decrease construction material costs, as it reduces reliance on natural resources such as natural coarse aggregate.

Numerical simulations of proppant transportation in cryogenic fluids: Implications on liquid helium and liquid nitrogen fracturing for subsurface hydrogen storage

The over dependence on fossil fuels for human energy requirements together with the resultant adverse environmental effects in the form of greenhouse gas discharges has redirected our attention towards renewable energy sources. Researchers have identified hydrogen, a non-carbonaceous energy source holding the capacity to substitute fossil fuels, as a viable fuel option that has the potential to be generated utilizing eco-friendly techniques. Studies have identified underground sites that are operational or have the potential to be used for hydrogen storage. Shale formations, characterized by their low permeability, offer promising opportunities for underground hydrogen storage. These formations require stimulation techniques to generate flow channels. Pumping frac-fluid into these formations at high pressure induces fractures in them and the engineered fractures are supported by the proppants injected along with the fluid. Propped fractures form a vital conduit in unconventional gas reservoirs, which are a potential medium for storage of hydrogen. Cryogenic fracturing is an innovative approach that aims to enhance and broaden the capabilities of conventional hydraulic fracturing processes. The transmission and settlement of proppants are influenced by certain critical aspects including their density, size and volume fraction and fluid velocity, which are investigated in this contribution. This study incorporates water and cryogenic fluids like liquid nitrogen (LN2) and liquid helium (LHe) as fracturing fluids. The primary objective of this effort is to analyze proppant transportation phenomenon and the key influential factors in LN2 and LHe. The proppant volume fraction contour, equilibrium dune level (EqDL) and dune height (EqDH) data are illustrated in this research for better understanding of proppant migration. It was observed that when the fracturing fluid is given a higher velocity, the proppant grains experience increased drag force, causing them to penetrate deeper into the fracture. The desired range of proppant volume fraction for improved grain transmission was determined as 0.45 to 0.50 and the critical proppant density that significantly affected the EqDL as 187.2839 lb/ft3.

Fungal-mediated synthesis of silver nanoparticles: a novel strategy for plant disease management.

Various traditional management techniques are employed to control plant diseases caused by bacteria and fungi. However, due to their drawbacks and adverse environmental effects, there is a shift toward employing more eco-friendly methods that are less harmful to the environment and human health. The main aim of the study was to biosynthesize silver Nanoparticles (AgNPs) from Rhizoctonia solani and Cladosporium cladosporioides using a green approach and to test the antimycotic activity of these biosynthesized AgNPs against a variety of pathogenic fungi. The characterization of samples was done by using UV-visible spectroscopy, SEM (scanning electron microscopy), FTIR (fourier transmission infrared spectroscopy), and XRD (X-ray diffractometry). During the study, the presence of strong plasmon absorbance bands at 420 and 450 nm confirmed the AgNPs biosynthesis by the fungi Rhizoctonia solani and Cladosporium cladosporioides. The biosynthesized AgNPs were 80-100 nm in size, asymmetrical in shape and became spherical to sub-spherical when aggregated. Assessment of the antifungal activity of the silver nanoparticles against various plant pathogenic fungi was carried out by agar well diffusion assay. Different concentration of AgNPs, 5 mg/mL 10 mg/mL and 15 mg/mL were tested to know the inhibitory effect of fungal plant pathogens viz. Aspergillus flavus, Penicillium citrinum, Fusarium oxysporum, Fusarium metavorans, and Aspergillus aflatoxiformans. However, 15 mg/mL concentration of the AgNPs showed excellent inhibitory activity against all tested fungal pathogens. Thus, the obtained results clearly suggest that silver nanoparticles may have important applications in controlling various plant diseases caused by fungi.

Evolutions of sustainable supply chain management in emerging economies: A literature review

The escalating demand for items and their consumption has exerted immense pressure on industrial production and supply chain systems, leading to adverse environmental and societal consequences. The rise in pollution rates and ecological disasters resulting from industrial production has prompted numerous scholars and industry specialists to focus on Sustainable Production and Consumption matters within the framework of Sustainable Supply Chain Management (SSCM). The interest in sustainable supply chain management has significantly increased in recent years, spanning both business and academic sectors. This phenomenon is seen in the growing prevalence of papers, conferences, specialized periodicals, and websites exclusively focused on the subject matter. Nevertheless, the importance of sustainable development in developing economies has only just started to be acknowledged. This literature review aims to assess existing research on sustainable supply chain management (SSCM) in developing nations while considering a worldwide perspective. This paper thoroughly examines the rapid expansion of the subject from an evolutionary perspective; aimed at comprehending the progression of sustainability concerns by examining patterns across different industries, and economies, and employing diverse approaches. An extensive thematic analysis was conducted on 56 selected publications published between 2010 and 2023, emphasizing the growth and significance of the knowledge base. The analysis is conducted utilizing a descriptive and content-oriented methodology. Subsequently, the results are presented, demonstrating an increasing interest in Sustainable Supply Chain Management (SSCM). Nevertheless, there is a conspicuous discrepancy in the extent of research carried out on this subject in emerging economies as opposed to industrialized ones. The findings indicate that the context in less developed countries plays a crucial role in carrying out empirical or case study research. Moreover, it is crucial to analyze how the integration of the three dimensions of sustainability impacts the efficiency of the supply chain, especially when considering the perspective of an emerging economy. Hence, the limitations of this investigation are delineated. Ultimately, it is crucial to do further research from multiple angles within the supply chain, encompassing collaboration, sustainable practices, innovation, sourcing, and supplier growth, with a special emphasis on the position and background of rising countries.

Unveiling the Invisible Threat: A Review of Heavy Metal Exposure and its Devastating Health Consequences

The widespread of heavy metals in air, soil, and water is a grave concern that poses a significant global threat. The distribution of contaminants such as mercury, lead, and cadmium are widespread and are associated with serious health risks such as cancer, cardiovascular and respiratory diseases, and Alzheimer's disease. Exposure to these heavy metals is known to cause numerous adverse health and environmental consequences, including toxicity from mercury and arsenic, neurological impairments caused by lead, and acute and chronic effects on various ecosystems, including birds, fish, and other species. This comprehensive review aims to highlight potential routes of exposure to the three most common heavy metal pollutants - mercury, cadmium, and lead - focusing on their uptake through drinking water, ambient air, and dietary sources. The review will delve into the mechanisms by which these metals enter the body and the various health implications associated with their exposure. Understanding how these metals enter the body and the negative effects they cause, emphasizes the need for effective mitigation strategies and stricter regulations to protect human health and safeguard the environment.

Impact of bio-fertilizers on growth, yield and quality of Spinach (Spinacia oleraceaL.) in Noida UP.

A field trial was undertaken at Amity University Noida’s experimental farm to investigate the effectiveness of microbial consortia on plant development and yield characteristics of spinach (Spinacia oleracea L.). Azotobacter, poultry manure, vermicompost, and FYM were used in various combinations throughout the treatments. The Desi (indigenous) variety was used in the field investigation. The use of biofertilizers is intended to increase crop yield and soil fertility while minimising environmental damage. The purpose of this study is to investigate the effects of various biofertilizers on the growth and yield of spinach (Spinacia oleracea L.) plants. These fertilisers include vermicompost, farmyard manure, Azotobacter, and poultry manure. The experiment was conducted out under closely monitored settings, with a randomised complete block design and three replications. Growth metrics were examined during the experiment to evaluate the vegetative growth of spinach plants, including plant height, leaf area, leaf length, and number of leaves per plant. The study’s findings demonstrated that the various treatments that were applied had a discernible impact on the growth, production, and economics of spinach. According to early data, the usage of biofertilizers considerably affected the growth and yield of spinach plants when compared to the control group. In comparison to the control, which had plant height (26.4 cm), leaves number (14), length of the leaves (15cm), leaves width (8cm), area of leaf per plant (120 cm2), and yield (4.5 Kg) the combined application of (Azotobacter + farmyard manure + poultry manure) demonstrated the highest performance on plant growth parameters such as height of the plants (35.4cm), leaves number per plant (16.7cm), leaves length (22cm), leaves width (12cm), and leaf area per plant (264 cm2). Furthermore, as seen by higher nutrient levels and organic matter content, the application of biofertilizers significantly improved soil fertility. This research present to the growing body of valuable information on sustainable farming practices by elucidating the efficacy of biofertilizers in enhancing the spinach growth and yield. The findings highlight how important it is to incorporate biofertilizers into agricultural practices to enhance soil health, reduce adverse environmental effects, and ensure the production of food sustainably.

Environmental Sustainability in Nigerian Manufacturing Industries: A Life Cycle Assessment of Production Processes

This journal examines the environmental sustainability practices within Nigerian manufacturing industries, focusing on a life cycle analysis (LCA) of their production processes. The study evaluates the environmental impacts at various stages of production, identifies key areas for improvement, and provides recommendations for enhancing sustainability. The findings underscore the importance of adopting comprehensive LCA methodologies to mitigate adverse environmental effects and promote sustainable industrial development.

CRISPR/Cas9-Mediated Genome Editing in Indica Rice (Oryza sativa L. subsp. indica var. CR-5272).

Tissue culture optimization protocols limit indica rice breeding. Such a challenge is vital because emergent techniques still rely on tissue culture methods and could allow the breeding of new varieties with higher production and toleration of adverse environmental effects caused by climate change. Genome editing technology, using CRISPR/Cas9, is a fast and precise method for accelerated plant breeding. It limited its use in indica subspecies because of the recalcitrant response to in vitro culture methods. This chapter describes a protocol for CRISPR/Cas9 editing in indica subspecies, specifically in the CR-5272 variety derived from parental lines IR-822, using Agrobacterium tumefaciens and biolistic transformation.

РЕАКТИВНОСТЬ ВЕГЕТАТИВНОЙ НЕРВНОЙ СИСТЕМЫ ПРИ НЕБЛАГОПРИЯТНЫХ ВОЗДЕЙСТВИЯХ

The study aims to determine how the reactivity of the autonomic nervous system contributes to the body’s multidrug resistance to adverse environmental effects. Volunteers were subjected to hypoxia simulation in an altitude chamber at 4 500 m and hyperthermia simulation by being exposed to a heating microclimate (40°, humidity 60–70 %). A spectral analysis of heart rhythm was used during a 5-minute continuous ECG recording to assess the characteristics of autonomic regulation. Regular changes in the frequencies and amplitudes of the leading peaks of the Fourier analysis of heart rate variability were revealed, indicating a rapid onset of the activity of the diencephalic centers of autonomic regulation and endocrine peripheral influences under adverse environmental conditions. The activity of parasympathetic regulation centers either was reduced or did not show significant dynamics. The study detected correlations between changes in the parameters of the spectral analysis of the heart rhythm and the main indicators of the state of the central nervous system, emodynamics, and pulmonary ventilation in healthy volunteers exposed to hypoxia or hyperthermia. Thus, it is possible to consider the reactivity of autonomic regulation as a modifying factor in the body’s resistance to extreme effects.