Adverse Circumstances Research Articles

Over-Produced Extracellular Polymeric Substances and Activated Antioxidant Enzymes Attribute to Resistance of Pb(II) for Algal–Bacterial Granular Sludge in Municipal Wastewater Treatment

Algal–bacterial granular sludge technology is a new type of wastewater treatment and resource regeneration process, which has received widespread attention due to its excellent nitrogen and phosphorus removal performance, and energy-saving and emission reduction effects. Although algal–bacterial granular sludge technology has achieved an ideal nutrient removal ability, some pol-lutants in wastewater might affect the symbiotic relationship between algae and bacteria. This study investigated the impact of coexisting Pb(II) on the symbiosis of algal–bacterial granular sludge. It was found that 2.5–10.0 mg/L of Pb(II) exposure increased the relative abundance of Pro-teobacteria. In addition, more protein in extracellular polymeric substances (EPS-PN) was secreted at 2.5 mg/L of Pb(II) exposure while EPS-PN content reduced at a rate of 5.0–10.0 mg/L of Pb(II). Under different concentrations of Pb(II), the damage degree of algal–bacterial granular sludge was exacerbated, evidenced by increased malondialdehyde (MDA) content. To cope with these adverse circumstances, the antioxidant enzyme activity of both super-oxide dismutase (SOD) and peroxidase dismutase (CAT) was boosted. With the help of these adaptive strategies, the symbiosis of algal–bacterial granular sludge was stable. Moreover, the performance of algal–bacterial granular sludge in treating COD, ammonia-N and phosphate-P was kept at above 95%. This study approved that a Pb(II) concentration less than 10.0 mg/L had little effect on the performance of algal–bacterial granular sludge in wastewater treatment. It is hoped that this study can provide useful information for an improved engineering feasibility of algal–bacterial granular sludge process.

Assessing populations exposed to climate change: a focus on Africa in a global context

The recent debate on population dynamics and climate change has highlighted the importance of assessing and quantifying disparities in populations’ vulnerability and adopting a forward-looking manner when considering the potential impacts of climate change on different communities and regions. In this article, we overlay demographic projections based on the Shared Socioeconomic Pathways and climate change projections derived from the Representative Concentration Pathways. We focus on populations that are likely to be the most exposed to climate change in the future, namely, African populations in a comparative global context. First, we estimate the share of populations living in rural areas, who would be more dependent on agriculture, as one of the economic sectors mostly affected by climate change. Second, we explore how climate change would worsen the condition of populations living below the poverty line. Finally, we account for low levels of education, as further factors limiting people’s adaptation ability to increasingly adverse climate circumstances. Our contribution to the literature on population, agriculture, and environmental change is twofold. Firstly, by mapping the potential populations exposed to climate change, in terms of declining agricultural yields, we identify vulnerable areas, allowing for the development of targeted strategies and interventions to mitigate the impacts, ensure resilience, and protect the population living in the most affected areas. Secondly, we assess differentials in the vulnerability of local populations, showing how African regions would become among one of the most exposed to climate change by the end of the century. The findings support the targeting of policy measures to prevent increased vulnerability among already disadvantaged populations.

Family economic status and vulnerability to suicidal ideation among adolescents: A re-examination of recent findings

BackgroundAccording to the “differential vulnerability hypothesis,” individuals in adverse socioeconomic circumstances as less mentally resilient to stressful events. However, several recent papers radically challenged this hypothesis based on the accumulated literature on stress inoculation and presented cases in which lower-SES adolescents appear to be less vulnerable to suicidal ideation in the face of interpersonal aggression. ObjectiveWe re-examine the link between psychological vulnerability to acute stressors and SES using yearly longitudinal public survey data from South Korea. Participants and settingThis is a secondary data analysis of a multi-year public health panel dataset on South Korean adolescents. MethodsLogistic regression is used to examine the association between suicidal ideation and a range of predictor variables, with a particular focus on the interaction between bullying victimhood and log family income. These variables and the sample were chosen for consistency with recent revisionist research. ResultsWe reaffirm the well-established finding that bullying victimhood strongly and consistently increases the odds of suicidal ideation (OR = 1.859, p < 0.01). However, we find no evidence in favor of the traditional “differential vulnerability hypothesis” or the recently proposed counterhypothesis. A subsample analysis from the latest wave (W4–W5) did produce results that are consistent with recent revisionist findings, but we suggest this is likely a false positive. ConclusionsThere appears to be no systematic association between SES and vulnerability to suicidal ideation in the face of peer aggression among South Korean adolescents. The claim that lower-SES adolescents may be more resilient to stressful events stands on limited empirical support.

Literacy and Liberation in Baby Halder’s A Life Less Ordinary

Autobiographical narratives offer a platform for marginalised voices to express their experiences. A Life Less Ordinary, translated into English in 2006, portrays the life experiences of Baby Halder and sheds light on the experiences of Dalit women. Born into a poverty-stricken family, Halder is forced into marriage and motherhood — a reflection of the expectations imposed on women in her community. The title of the memoir underlines the remarkable journey of a marginalised woman who is anything but ordinary. Due to adverse circumstances, Halder was compelled to leave her home and venture out in search of employment. Becoming a domestic worker helped her earn a living. Her book takes us on a turbulent journey from a childhood in a broken family to being forced into marriage at the tender age of twelve, enduring an abusive husband, and ultimately defying societal norms by leaving him and starting work outside her household. According to Ranajit Guha’s definition of the subaltern, Baby Halder embodies three “attributes of subordination”: gender, caste, and poverty. Halder’s wish to fill the gap left in her formal education motivated her to read and write her life story. This paper explores how literacy opens up opportunities for knowledge, self-discovery, and critical thinking, enabling her to question and challenge the norms that once defined her life. It showcases how education can bring about transformation in the life of a marginalised woman striving for personal and social liberation.

Servant Leadership, Cultural Dimension, and Adversity Quotient: A Causal Model on Organizational Resilience of the Local Government Units’ Employees in Davao Region

Purpose: The study aimed to determine the best-fit model for organizational resilience of local government unit employees regarding servant leadership, cultural dimension, and employees' adversity quotient. The descriptive-causal method and non-experimental quantitative research design were applied. Organizations considerably give these effects of the worrying manifestations attention to guarantee social support in times of need. Resilient leaders should have access to trusted peers and social groups, time, reflection, collaboration, and conversational development chances that request to reduce social seclusion and more chances for partnerships. In this context, the researcher was prompted to conduct the study to determine whether servant leadership, cultural dimension, adversity quotient, and the employees' resilience, especially in local government units, should be strengthened in response to adverse circumstances. Therefore, this would fill the gap, as supported by the literature regarding the local setting.&#x0D; Methodology: Three hundred ninety-three employees from six cities in Davao Region were surveyed using standardized adapted instruments. The survey questionnaire used was validated and approved by experts. The respondents were selected through a stratified sampling technique. Data were analyzed using the Mean, Pearson r, Regression Analysis, and Structural Equation Modeling.&#x0D; Findings: Results revealed that all variables gained a very high level. The result of the study also revealed an overall significant relationship and influence between the exogenous and endogenous variables. Furthermore, the best-fit model for organizational resilience was generated and demonstrated a direct effect in Model 5, and the goodness of fit measures' requirements were met. It is detected that there is a correlation between the exogenous and Endogenous variables. The important relationship between the exogenous and endogenous variables, which predicts the study's findings, is a pronouncement that being resilient and adverse to a chaotic situation could be effective and useful to withstand an employee's life&#x0D; Recommendations: The suggestion between the Exogenous and Endogenous in creating organizational resilience in municipal governments should be essentially measured. This is recommended to the Human Resource Management that embraces and exercises the practice of being efficient in their work and responsibilities to impart individual adversity consciousness and cultivate the employees from training and development.

Associations between social adversity, caregiver psychological factors, and language outcomes in 9.5-year-old children born to women with opioid use disorder

ABSTRACT We describe the language ability of children at age 9.5 years who were born to women with an opioid use disorder and examine the associations between prenatal opioid exposure, sex, social adversity, caregiver psychological factors, and child language. Data were drawn from the regional prospective longitudinal Canterbury Methadone in Pregnancy study. At the 9.5-year wave, 80 children who were born to mothers in Methadone Maintenance Treatment and their caregivers, and 98 non-exposed comparison children were assessed using a comprehensive standardized measure of language. Information related to social adversity and caregiver psychological factors was obtained from comprehensive caregiver interviews. At age 9.5 years, opioid-exposed children had lower language scores than the non-exposed children, however their group average was within the normal range on the CELF-4 norms. A series of multivariate hierarchical regression models predicting low language at 9.5 years showed sex and opioid-exposure status predicted low language in the first step. The addition of social adversity factors significantly improved the model. The further addition of caregiver psychological factors did not improve prediction. Only sex was a significant predictor throughout. In this sample, children prenatally exposed to opioids were at higher risk of low language outcomes. However, the child being male and social adversity were important influencing factors. This suggests early language support services are indicated for opioid-exposed children, particularly boys and those in socially adverse circumstances.

Tüm Zorluklara Rağmen Hayatta Kalmak: Deniz Rizikoları Karşısında Cesaret ve Dayanıklılığın Sürükleyici Bir Hikayesi

Resilience theory, a concept rooted in psychology, refers to the human potential to react to and adjust to adverse circumstances. In extreme circumstances, resilience becomes crucial as it enables individuals to overcome challenges and ultimately survive. In the novel Adrift: Seventy-six Days Lost at Sea by Steven Callahan this theory takes a central stage and portrays the struggles faced by the writer at sea after a catastrophic shipwreck. During his journey, Callahan faces numerous obstacles including severe weather conditions, the risk of dehydration and starvation, as well as limited resources. His unshakeable resolve and determination are put to test further and further with each passing day, as he struggles to adjust to his harsh surroundings. In fact, his unwavering commitment to optimism outlook also serves as a guiding light in his voyage through the vast ocean of life. This paper will analyze Callahan’s journey in the light of resilience theory by examining the factors that contributed to his resilience, such as his ability to adapt to his surroundings, his mental and emotional strength, and his resourcefulness and his problem-solving skills. Additionally, by analyzing the protagonist’s psychological and emotional responses to his circumstances this paper will show how resilience can help individuals overcome challenges.

Russifi cation Policy Conceptual Framework Formation in the Western Borderland Regions in the Domestic Conservative Discourse on the Eve of the January Uprising of 1863

Incorporation into the Russian Empire in the 18th century of the eastern areas of the Polish- Lithuanian Commonwealth, that were according to Russian intellectuals and state fi gures integral parts of “Russian world” detached from it due to adverse historic circumstances, as well as annexation by the empire of native Polish lands in the beginning of the 19th century, led to the appearance in Russian socio-political discourse of the fatal “Polish issue”, connected not only with the necessity to ensure the Polish subjects loyalty but also with striving to integrate Western borderlands into the common imperial space. In the second half of the 1850ies and the beginning of the 1860ies the formation of conceptual basics of imperial policy in relation to the Western areas started in the national conservative circles, and the key element there was the necessity of the comprehensive area russifi cation, since the area was viewed as “original Russian’, but exposed in its development to substantial “distortions” related to the long-term Polonism domination. Russian intellectuals and state fi gures in the Western areas called for total Polonism extermination accompanied by concurrent development of “Russian fundamentals” that was supposed to be realized with the help of the combination of tough administrative steps and the policy of “soft power”.

Mind, Body, and Pandemic: Understanding the Complex Relationships Between Subjective Well-Being, Physical Activity, and Perceived Multi-Dimensional COVID-19 Impact

In response to the need for further research on factors influencing university students’ well-being during challenging circumstances, this study tests a potential mechanism to unravel the complex relationships between perceived impacts of COVID-19 on psychological health, academic performance, and financial status, subjective well-being, and physical activity. The main objective was to investigate these intricate associations among university students. A nationwide online survey involving 848 Greek-speaking university students (70.8% females, average age = 27.65) was conducted. The results revealed both direct effects of subjective well-being on participants’ perceptions of COVID-19 impact on their financial status and psychological health, as well as indirect effects mediated by physical activity. The study also examined gender and age effects. These findings emphasize the importance of empirically examining the outcomes linked to subjective well-being and provide supporting evidence that higher levels of subjective well-being can lead to positive consequences. By shedding light on the interplay between subjective well-being, perceived pandemic impact, and physical activity, this study enriches our understanding of how university students cope with adverse circumstances like the COVID-19 pandemic.

Viable but nonculturable (VBNC) state, an underestimated and controversial microbial survival strategy.

As a unique microbial response to adverse circumstances, the viable but nonculturable (VBNC) state is characterized by the loss of culturability of microbial cells on/in nutrient media that normally support their growth, while maintaining metabolic activity. These cells can resuscitate to a culturable state under suitable conditions. Given the intrinsic importance of the VBNC state and recent debates surrounding it, there is a need to redefine and standardize the term, and to address essential questions such as 'How to differentiate VBNC from other similar terms?' and 'How can VBNC cells be standardly and accurately determined?'. This opinion piece aims at contributing to an improved understanding of the VBNC state and promoting its proper handling as an underestimated and controversial microbial survival strategy.

SDR, EVC, and SDREVC: Limitations and Extensions

Methods for reducing the radius, temperature and space charge of a non-neutral plasma are usually reported for conditions which approximate an ideal Penning Malmberg trap. Here, we show that (i) similar methods are still effective under surprisingly adverse circumstances: we perform strong drive regime (SDR) compression and SDREVC in a strong magnetic mirror field using only 3 out of 4 rotating wall petals. In addition, we demonstrate (ii) an alternative to SDREVC, using e-kick instead of evaporative cooling (EVC) and (iii) an upper limit for how much plasma can be cooled to $T&lt;20\ \mathrm {K}$ using EVC. This limit depends on the space charge, not on the number of particles or the plasma density.

Exploring self-determined solutions to service and system challenges to promote social and emotional wellbeing in Aboriginal and Torres Strait Islander people: a qualitative study.

Many Aboriginal and Torres Strait Islander people living on Kaurna Country in northern Adelaide experience adverse health and social circumstances. The Taingiwilta Pirku Kawantila study sought to understand challenges facing Aboriginal and Torres Strait Islander communities and identify solutions for the health and social service system to promote social and emotional wellbeing. This qualitative study applied Indigenous methodologies undertaken with Aboriginal and Torres Strait Islander governance and leadership. A respected local Aboriginal person engaged with Aboriginal and Torres Strait Islander community members and service providers through semi-structured interviews and yarning circles that explored community needs and challenges, service gaps, access barriers, success stories, proposed strategies to address service and system challenges, and principles and values for service design. A content analysis identified the breadth of challenges in addition to describing key targets to empower and connect communities and optimize health and social services to strengthen individual and collective social and emotional wellbeing. Eighty-three participants contributed to interviews and yarning circles including 17 Aboriginal community members, 38 Aboriginal and Torres Strait Islander service providers, and 28 non-Indigenous service providers. They expressed the need for codesigned, strengths-based, accessible and flexible services delivered by Aboriginal and Torres Strait Islander workers with lived experience employed in organisations with Aboriginal and Torres Strait Islander leadership and governance. Community hubs and cultural events in addition to one-stop-shop service centres and pre-crisis mental health, drug and alcohol and homelessness services were among many strategies identified. Holistic approaches to the promotion of social and emotional wellbeing are critical. Aboriginal and Torres Strait Islander people are calling for places in the community to connect and practice culture. They seek culturally safe systems that enable equitable access to and navigation of health and social services. Aboriginal and Torres Strait Islander workforce leading engagement with clients is seen to safeguard against judgement and discrimination, rebuild community trust in the service system and promote streamlined access to crucial services.

Goats and their role in climate change

Goats are the primary source of protein for many rural communities worldwide, particularly those living in extreme geographical conditions. Goats have numerous advantages that enable them to maintain their production under extreme climate conditions. They have efficient browsing behavior as well as an efficient digestive system, allowing them to remain productive in difficult environmental circumstances. Strong heat resistance, outstanding feed conversion efficiency, survival in adverse climatic circumstances, and high resistance to many diseases are all traits that contribute to production. Because of these features, goat breeding is vital to minimizing and adapting to the negative consequences of climate change. Livestock production accounts for around 7–18% of anthropogenic greenhouse gas emissions. Of this, goats specifically account for 4% of overall greenhouse gas emissions in global animal farming. Enteric CH4 released during production is considered a nutritional energy loss in goats and it’s an important role in global warming and the greenhouse effect. These effects ensure that CH4 production is reduced to provide an optimum economic return from goat farming as well as reduce the impact on global warming. The capacity of goats to adapt to the negative impacts of climate change and their benefits in sustainable production compared to other ruminant species will be thoroughly examined in this paper. As a result, it will contribute to a better understanding of the benefits of goat breeding in the face of future climate change.

Nanotechnology and Nanocapsule-Based Approaches for the Diagnosis and Therapeutics of Diabetes Mellitus: A Concise Survey

A serious health concern of frightening proportions is diabetes mellitus, a common metabolic illness marked by increased blood sugar levels as a result of insufficient insulin production or response. Nanosensors and nanomaterials have recently shown tremendous promise for enhancing glucose detection for the treatment of diabetes. Significant improvements in glucose sensor sensitivity, specificity, and reversibility have been achieved through the incorporation of nanoscale carbon structures, nanocomposites, and other nanomaterials. The use of these tailored nanocarriers offers a viable technique to enhance patient compliance and diabetes management by addressing the difficulties associated with oral peptide medication delivery for the treatment of diabetes caused by adverse circumstances in the gastrointestinal system. Nanocapsules are a promising approach for effective medication transportation via biological barriers by protecting drug molecules from the biological environment. A workable solution to problems with oral peptide medicine distribution for treating diabetes, particularly when it comes to unfavorable gastrointestinal conditions, is the use of customized nanocarriers. These nanocarriers have a flexible design and special in vivo characteristics that make it possible to go beyond cellular and tissue absorption barriers while improving the stability and effectiveness of therapeutic peptides. The management of diabetes mellitus has a great deal of potential for targeted lipid-based nanoparticles, which operate as an efficient drug delivery technique for oral administration of therapeutic peptides. With these developments in nanotechnology and nanocapsule-based techniques, diabetes treatment might be improved, patient compliance could be increased, and drug administration frequency could be decreased, potentially changing the field. This article presents a comprehensive review of recent advances in nanotechnology for diabetes mellitus diagnosis and the utilization of nanocapsules in diabetes treatment&#x0D; Keywords: Nanotechnology, Nanocapsules, Diabetes Mellitus, Nanocarriers, Nanomaterial, Nanotube

Tencent Game Competitive Advantage Analysis

In 2019, COVID-19 swept the world, significantly blowing the Chinese and global markets. Maintaining market share has become the goal of Chinese and even global enterprises. Based on huge market research and data, a few enterprises are still maintaining growth momentum under the sluggish market environment, and the Tencent game is one of them. This article takes "Tencent Game Competitive Advantage Analysis" as the topic, selects Tencent Game as the research object, analyzes the online game industry environment using Porters five forces model, and analyzes Tencent Games competitive advantages from the aspects of research and development, marketing, operation, and anti-risk ability so that it remains in the leading position in the game market and still obtains much economic income in the face of adverse circumstances. By analyzing Tencents competitive advantages, it has great reference value and experience for the future development of other online game companies.

Proposal for the Follow-up of Newly Registered Students on the Part of Professionals from the Center for General Studies in the Post-pandemic Context

Considering the present juncture that the educational system is going thru after the Pandemic of Covid-19, which ultimately caused a series of restrictive measures by the Ministry of Education, and previously, by a series of strikes in the public sector, it was assumed that students of recent entrance in the Centre for General Studies (Centro de Estudios Generales, CEG) could present an educational lag. This could consequently generate some apprehension and uncertainty, and possibly wider student during the academic year 2020. Considering such eventuality, a special Conference titled in the same manner as this article was organized; such event was geared towards the educational and administrative body of the CEG with the main purpose of creating some bio-pedagogical instruments for sensitizing professors with respect to posible traumas of the new post-Pandemic students. In this article we present the essential basis of the Conference grounded upon the Theory of emotional intelligence by Daniel Goleman, as an ideal resource for confronting such adverse circumstances. All these aspects are approached using the bio-pedagogic emergent paradigm. First, we detail some contextual factors, and secondly we follow with the topic of educational lag, the basis for resilience, after critical events, emotional intelligence, and bio-pedagogical didactics.

New insights into the regulation mechanism of Pacific white shrimp (Litopenaeus vannamei) hepatopancreas under 4-nonylphenol exposure using transcriptome analysis

4-Nonylphenol (4-NP) is one of the common endocrine-disrupting chemicals (EDCs) in estuaries and coastal zones, which can exert detrimental effects on the physiological function of aquatic organisms. However, the molecular response triggered by 4-NP remains largely unknown in Pacific white shrimp (Litopenaeus vannamei). In this study, transcriptomic analysis was performed to investigate the underlying mechanisms of 4-NP toxicity in the hepatopancreas of L. vannamei. Nine RNA-Seq libraries were generated from L. vannamei at 0 h, 24 h, and 48 h following exposure to 4-NP. Compared with 0 h vs 24 h, 962 up- and 463 down-regulated differentially expressed genes (DEGs) were identified, indicating that many genes in L. vannamei were induced to resist adverse circumstances by 4-NP exposure. In contrast, 902 up- and 1027 down-regulated DEGs were revealed in the comparison of 0 h vs 48 h, demonstrating that prolonged exposure to the stress from 4-NP resulted in more inhibited genes. To validate the accuracy of the transcriptome data, eight DEGs were selected for quantitative real-time polymerase chain reaction (qRT-PCR), which were consistent with the RNA-Seq results. Through KEGG pathway enrichment analysis, three specific pathways related to hormonal effects and endocrine function of L. vannamei were enriched significantly, including tyrosine metabolism, insect hormone biosynthesis, and melanogenesis. After 4-NP stress, genes involved in tyrosine metabolism (Tyr) and melanogenesis pathway (AC, CBP, Wnt, Frizzled, Tcf, and Ras) were induced to promote melanin pigment to help shrimp resist adverse environments. In the insect hormone biosynthesis, ALDH, CYP15A1, CYP15A1/C1, and JHE genes were activated to synthesize juvenile hormone (JH), while Spook, Phm, Sad, and CYP18A1 were induced to generate molting hormone. There is an enhanced interaction between the molting hormone and JH, with JH playing a dominant role and maintaining its “classic status quo action”. Our study demonstrated that 4-NP exposure led to impairments of biological functions in L. vannamei hepatopancreas. The genes and pathways identified provide novel insights into the molecular mechanisms underlying 4-NP toxicity effects in prawns and enrich the information on the toxicity mechanism of crustaceans in response to EDCs exposure.

Resilience and post-traumatic stress disorder among healthcare workers during the COVID-19 outbreak

During the health emergency caused by the COVID-19 pandemic, one of the most affected sectors was the healthcare workers (HCWs), since it is a population group with a high risk of developing post-traumatic stress disorder (PTSD), anxiety, or depression. Resilience is one of the abilities that can favor a greater adaptation to adverse circumstances. Therefore, the aim of the present research was to know the association between resilience and PTSD in HCWs during the COVID-19 outbreak, which contributes to the development of preventive strategies and therapeutic interventions for this debilitating mental disorder. The study was prospective ex post facto, cross-sectional; it had a non-probabilistic sample of 613 Mexican HCWs. Data was collected through the platform www.personalcovid.com. The results obtained showed that resilience is negatively related to PTSD, with nurses being the most at-risk group among HCWs.

Hispanic/Latinx College Students’ Mental Health During the COVID-19 Pandemic: The Effects of Familismo and Self-Efficacy

ABSTRACT Hispanic/Latinx student enrollment in U.S. colleges has increased over the last decade; however, disparities in degree completion still exist. Hispanic/Latinx college students experience a variety of challenges, including cultural stressors, that when compounded with stressors associated with the COVID-19 pandemic, further increase the risk for academic and mental health problems. Familismo and self-efficacy are protective factors for Hispanic/Latinx student mental health; yet their main and interaction effects in unique adverse circumstances, such as a global pandemic, are not yet well understood. Using survey data from a sample of Hispanic/Latinx college students, this study examined the impact of familismo, self-efficacy, and their interaction on mental health during the ongoing COVID-19 pandemic. Although results suggest that the main effects of familismo and self-efficacy are associated with fewer days during which students experienced mental health symptoms, the interaction between familismo and self-efficacy was associated with more days during which mental health symptoms were experienced. Study findings have implications for the development and implementation of culturally sensitive and responsive mental health and educational services for Hispanic/Latinx college students.

Aging with spinal cord injury: A narrative review of consequences and challenges.

Given the increase in life expectancy, aging with a pre-existing spinal cord injury (SCI) is becoming more common. This condition is challenging as compromised health status and functional independence can worsen. We aimed to provide an updated overview of the consequences of aging with SCI, highlighting the main challenges facing this population in a narrative review of the current literature we retrieved from the PubMed database from 2000 to 2022 on any aspect related to aging in persons with SCI. Here we address adverse circumstances that increase disability and hinder an active lifestyle, such as progressive physical deterioration, secondary health conditions, limitations in personal activity, changes in family and social support structures, aging of caregivers, and depletion of economic resources. Favorable changes are also observed, including psychosocial adjustments that improve quality of life. Additionally, various interventions are discussed to promote well-being, health, and social participation. Due to the relevance of this issue, people with SCI and all those who take care of them must have up-to-date information to carry out the necessary measures to promote healthy aging in a more inclusive social environment.