The technological progress in the field of artificial intelligence (AI) has brought new opportunities and challenges to the intelligent development and innovative research in fuzzy spatial relations, fuzzy theory is the basic theory of intelligent information processing, and the paper gives a brief analysis of fuzzy calculation method in spatial analysis and spatial relation calculation. In particular, the spatial relations of fuzzy objects are more difficult to express and describe accurately. This paper proposes a method to calculate the topological relations between fuzzy objects with 4-Intersection model and 9-Intersection model, in the analysis of spatial relations, the extension from deterministic entity to uncertain entity is realized with fuzzy set theory, the fuzzy space matrix is constructed, then fuzzy topological relations and fuzzy membership are calculated and output, the model simplifies many complex relations, and it can describe eight topological relations including disjoint, meet, overlap, covers, contains, covered-by, inside and equal. In practical application, the position of spatial objects can be controlled and adjusted according to topological relations. Through analysis of algorithm and fuzzy membership calculation, the model is effective in theory.