WITHDRAWN: Determination of ampicillin in pharmaceutical preparations by molecularly imprinted polymer in PVC matrix membrane

Abstract

This revision was grounded on creating four electrodes based on molecularly imprinted polymers (MIPs). Were Ampicillin sodium was used (AMP-Na) as the template, 1-vinyl imidazole (VIZ) and vinyl acetate (VA) as monomer, and N, N-methylene bis acrylamide (MBAA) as cross-linkers and benzoyl peroxide as the motivator, two MIPs were set. The same composition was used in the preparation of non-impressed polymers (NIPs), but without the template (Ampicillin sodium). For the preparation of membranes, Numerous plasticizers, such as tri-poly phosphate (TOP) and dactyl phthalate (DOP), were used in the PVC matrix. Slop, recognition limit, lifetime, and linearity variety of AMP- MIPs electrodes are the study’s characteristics. There’s no contact with the Amoxicillin sodium drug in the obtained results from selectivity measurements on inquisitive cations (K+, Ca + 2, Al + 3) and certain pharmaceutical additives such as methyl paraben, propyl paraben and tri sodium citrate. Electrodes preparation have presented decent response including testing of pharmaceutical analysis.