Abstract

Transverse dimensions of the body as morphogenetic markers within the constitutional integrity of the organism involve the identification of their connection with the adaptive abilities of man and they are studied in the process of ontogenesis under the influence of the environment. Establishing the patterns of intersystem connections will further develop a system of criteria for prognostic assessment of the risk of seborrheic dermatitis based on the phenotypology of human body parameters. The aim of the study was to establish and analyze the features of the width of the distal epiphyses of the long tubular bones of the extremities and the transverse diameters of the body in men and women with seborrheic dermatitis of varying severity. The width of the distal epiphyses of the long tubular bones of the extremities and transverse diameters of the body in 40 men and 40 women (aged 25 to 44 years) with generalized fatty seborrheic dermatitis (mild and severe) were determined. The control group consisted of indicators of the width of the distal epiphyses of long tubular bones of the extremities and transverse body diameters of practically healthy men (n=82) and women (n=154) of the same age group, selected from the National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of body circumference was performed in the licensed package "Statistica 6.0" using non-parametric estimation methods. As a result of studies in patients with seborrheic dermatitis of varying severity of men, compared with practically healthy men, found only greater values of transverse middle thoracic diameter, anteroposterior middle sternal diameter, intertrochanteric distance, as well as smaller values of shoulder width and distal shoulder width; and in patients of varying severity of women – in almost all cases (except for the width of the distal epiphysis of the shoulder) found greater values of the width of the distal epiphyses of the long tubular bones of the limbs and transverse body diameters (except shoulder width). Moreover, both in sick men and women, differences in transverse body size are more pronounced in people with severe seborrheic dermatitis. Among men or women with seborrheic dermatitis of varying severity, there is only a tendency for greater values in women with severe transverse lower thoracic diameter and intertrochanteric distance, and in men with severe – a tendency to greater values of the distal forearm width. There are also pronounced manifestations of sexual dimorphism of the width of the distal epiphyses of the long tubular bones of the limbs and transverse diameters of the body (except for pelvis sizes), namely – higher values of these indicators in patients with seborrheic dermatitis of varying severity.

Highlights

  • According to modern epidemiological studies, seborrheic dermatitis is a fairly common chronic dermatosis

  • Seborrheic dermatitis rarely leads to disability or death of the patient, but significantly impairs the quality of life of the patient, his social and occupational adaptation

  • On the basis of the Department of Dermatology and Venereal Diseases with a postgraduate course in National Pirogov Memorial Medical University, Vinnytsia and the Military Medical Clinical Center of the Central Region conducted a survey of 40 men and 40 young women (2544 years according to W HO age period, 2015) patients with generalized fatty seborrheic dermatitis

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Summary

Introduction

According to modern epidemiological studies, seborrheic dermatitis is a fairly common chronic dermatosis. In the world population, regardless of ethnic, climatic, geographical, socio-economic, sexual factors, there is an increase in the incidence of seborrheic dermatitis, and an increase in the severity of severe, resistant to treatment [3]. Seborrheic dermatitis rarely leads to disability or death of the patient, but significantly impairs the quality of life of the patient, his social and occupational adaptation. The basis of clinical manifestations of seborrheic dermatitis is hyperkeratosis, necrosis of keratinocytes of varying severity. Increased reproduction of epidermal cells with a violation of the process of differentiation leads to the formation of a defective stratum corneum on the background of inflammatory phenomena in the dermis [12]

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