Transverse body sizes in men with benign nevi

Abstract

Annotation. Malignant and benign skin neoplasms are multifactorial diseases, the development of which is perhaps most related to environmental factors. The search for constitutional markers for predicting the occurrence of these cancers has become one of the most promising areas of research in the field of oncology. The aim of the study was to establish the features of transverse body sizes in Ukrainian men with benign nevi. In Ukrainian men (aged 22-35 years) with benign nevi (melanocyte simple – 34, melanocyte dysplastic – 27, melanocyte congenital – 14 and non-melanocyte benign – 17), body diameters and pelvic sizes were determined. The control group consisted of similar size 82 healthy men from the database of the research center National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. Practically healthy Ukrainian men had significantly lower values than men with benign nevi, transverse middle thoracic, lower thoracic and anteroposterior mid-sternal torso diameters on the background of significantly greater shoulder width. Also in practically healthy men interspinous, intercristal and intertrochanteric distances are significantly smaller than in patients with melanocyte benign simple nevi, and only interspinous and intercristal distances are compared to non-melanocyte benign nevi. In patients with melanocyte simple nevi of men found: significantly higher values than in patients with melanocyte dysplastic nevi of transverse middle thoracic and lower thoracic diameters and all pelvic distances; significantly greater or tendency to greater values than in patients with melanocyte congenital nevi intercristal and intertrochanteric distances; significantly lower values than in patients with melanocyte congenital and non-melanocyte benign shoulder-width nevi. In patients with melanocyte dysplastic nevi found: significantly less important than in patients with melanocytic congenital nevi shoulder-width; tendencies to lower values than in patients with non-melanocyte benign nevi of transverse lower thoracic diameter, shoulder width and interspinous distance. The differences in body diameters and pelvic sizes between healthy and benign nevi in Ukrainian men, as well as between sick men are phenotypic markers that, together with other anthropometric indicators, identify risk groups for the possibility of benign nevi.