Abstract

Today in modern medicine the study of human health is reoriented to the individual principle, which is based on the identification and study of constitutionally determined patterns of manifestation of certain diseases. The purpose of the study is to establish and analyze the features of the girth body sizes in men and women with generalized fatty form of seborrheic dermatitis of varying severity. The comprehensive body size of 40 men and 40 young women (25-44 years) with generalized fatty seborrheic dermatitis (mild and severe) was determined. The control group consisted of the girth sizes of practically healthy men (n=82) and women (n=154) of the same age group, which were selected from the database of the research center National Pirogov Memorial Medical University. Statistical processing of body circumference was performed in the licensed package “Statistica 6.0” using non-parametric evaluation methods. As a result of studies in patients with seborrheic dermatitis of varying severity of men, compared with practically healthy men, found only greater values of the girth of the shoulder in a relaxed state and thighs, neck (only mild), shin in the upper part and waist (in both cases only with a severe degree), as well as smaller values of the girth of the shoulder in a tense state; and in patients of varying severity of women – greater values of the girth of the shoulder in a relaxed state, thighs, lower legs, neck, waist and all girths of the chest and both thighs (only severe), as well as smaller values of the girth of the hand (only with mild). In both men and women with seborrheic dermatitis, differences in girth body sizes are more pronounced in people with severe disease. Between men or women with seborrheic dermatitis of varying severity, there are no significant or trends in differences in girth body sizes. In the analysis of the manifestations of sexual dimorphism of the circumferential body size between men and women with seborrheic dermatitis found greater values in men with mild and severe disease of the upper extremities, hands, shin, feet and neck (in most cases more pronounced in representatives with mild severity), as well as only in men with mild severity – greater values of all chest girths. For a more correct understanding of changes in girth body sizes in Ukrainian men or women with seborrheic dermatitis of varying severity, it is necessary to analyze other constitutional parameters of the body.

Highlights

  • The problem of diseases with a chronic long course is currently quite relevant in both theoretical and practical terms [2, 7].Seborrheic dermatitis belongs to multifactorial diseases with complex and multifaceted pathogenesis

  • The work of recent years reflects the participation in the pathogenesis of dermatosis of almost all integrating systems of the body and the main parts of its basic functional systems

  • Given the most common manifestation of seborrheic dermatitis in young working age and in a third of cases severe, continuously recurrent course, the presence of many therapeutic approaches, none of which guarantees the effect of treatment and the absence of recurrence, there is a need to seek prognostic exacerbations [13, 19, 20]

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Summary

Introduction

The problem of diseases with a chronic long course is currently quite relevant in both theoretical and practical terms [2, 7].Seborrheic dermatitis belongs to multifactorial diseases with complex and multifaceted pathogenesis. The work of recent years reflects the participation in the pathogenesis of dermatosis of almost all integrating systems of the body and the main parts of its basic functional systems. Both exogenous (physicochemical, biological) and endogenous (nervous system, genetic predisposition and immune disorders) factors are involved in the phenotypic manifestation of this disease. Given the most common manifestation of seborrheic dermatitis in young working age and in a third of cases severe, continuously recurrent course, the presence of many therapeutic approaches, none of which guarantees the effect of treatment and the absence of recurrence, there is a need to seek prognostic exacerbations [13, 19, 20]

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