Therapeutic effect of two threapies for bronchial asthma complicated with allergic rhinitis

Abstract

Objective To compare therapeutic effects of fluticasone propionate aerosol combined with fluticasone nasal pray and alone fluticasone propionate aerosol for bronchial asthma complcated with allergic rhinitis.Methods Fifty asthmatic children with allergic rhinitis were randomly divided into observation group and control group.Observation group were treated with fluticasone propionate aerosol combined with fluticasone nasal pray,control group were treated with fluticasone propionate aerosol alone.All the patients were observed for 6 months.The lung function parameters( FEV1％ ),the number of acute asthma symptom,the number of days without acute asthma symptom,the number of acute allergic symptoms at one month,three months,six months after the treatment.were observed.Results FEV1％of observation group were(107.2 ± 15.3)％,( 115.3 ± 11.9)％,( 131.3 ± 10.9)％,and were significantly improved(98.6 ± 13.6)％,( 102.6 ± 13.6)％,( 126.5 ±9.7)％ 、(t =2.306,3.355,3.714,all P ＜0.05) at one month,three months,six months after the treatment.The number of acute asthma symptom,the number of days without acute asthma symptom,the number of acute allergic symptoms of observation group were(0.13 ±0.11),(150.2 ±14.3),(0.25 ±0.31),and control group were(0.30 ±0.44),(116.5 ±23.1),(0.65 ±0.24),Observation group had significant difference compared with control group(t =2.413,3.435,3.734,all P ＜0.05).Conclusion There was significant therapeutic effect of fluticasone propionate aerosol combined with fluticasone nasal pray for bronchial asthma complicated with allergic thinitis,and was worthy of clinical application Key words: Asthma; Rhinitis, allergic; Fluticasone