Abstract
Objective To study the significance of serum ischemia modified albumin(IMA) and brain natriuretic peptide(BNP) in patients with acute coronary syndrome. Methods Patients with acute coronary syndrome in six hours were divided into ST elevation myocardial infarction(STEM) of forty one cases, non-ST elevation myocardial infarction( NSTEM)of forty four cases and unstable angina of forty three cases. Twenty healthy people were selected as the control group. The serum IMA and BNP were detected. Results The levels of IMA and BNP in STEM group [(89. 6 ± 21.4) ABSU/ml, ( 324. 6 ± 39. 1 ) ng/L] were significantly higher than those in NSTEM group [( 79. 3 ±20. 5) ABSU/ml, (259. 7 ± 30. 5) ng/L]. The levels of IMA and BNP in NSTEM group were significantly higher than those in UA group[(67. 1 ± 18. 3)ABSU/ml,(124. 1 ±24. 3)ng/L].The levels of IMA and BNP in UA group were significantly higher than those in control group [( 56. 2 ± 15. 1 ) ABSU/ml, ( 15.9 ± 6. 7 ) ng/L]. Conclusion The levels of IMA and BNP in serum could forecast severity in patients with acute coronary syndrome. Key words: Acute coronary syndrome; Ischemia modified protein; Natriuretic peptide, brain
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