The safety and feasibility analysis of viaminate capsule in the treatment of seborrheic dermatitis

Abstract

Objective To investigate the safety and feasibility of viaminate capsule in the treatment of sebor-rheic dermatitis.Methods According to the digital table, 84 patients with seborrheic dermatitis were randomly divided into the observation group（n=42） and the control group（n=42）.The control group were treated with 1%pimecrolimus cream coated, 2 times/d.The observation group were treated with capsule viaminate, 50mg/times, 2 times/d,2 weeks for a course of treatment.The clinical efficacy of the two groups were observed.Results The ery thema,scaling,seborrhea,itching and other symptoms score and total score after treatment to 4 weeks,8 weeks of the two groups were compared（Erythema t=5.865,5.786;scaly t=6.112,5.886;seborrhea t=5.963,5.629;itching t=6.123,6.072.all P〈0.05）.The total effective rate of treatment 1 week,4 weeks,8 weeks of observation group were 57.14%,85.71%,95.24%.The control group were 42.86%,59.52%,80.95%,the difference was statistical-ly significant（χ2 =5.632,6.986,5.252,all P 〈0.05）.The patients relapse rate of the observation group was 2.38%,which was lower than 19.05%of the control group（χ2 =5.986,P〈0.05）,and the satisfaction rate of the observation group was 100.00%,which was higher than 76.19%of the control group（χ2 =6.123,P〈0.05）,but the adverse effects of the two groups had no statistically significant（χ2 =0.589,P〉0.05）.Conclusion Viaminate cap-sule can improve in a short period of time in patients with clinical symptoms of seborrheic dermatitis,the effect is sig-nificant,the recurrence rate is low,safe and effective. Key words: Dermatitis; Seborrheic Viaminate Capsules