The long-term effect of iodine-131 treatment of hyperthyroidism

Abstract

Objective To study the clinical effect of iodine-131 treatment of hyperthyroidism. Methods 92 hyperthyroidism patients were selected,who were randomly divided into the observation group and control group,with each 46 cases.The observation group was given radioactive iodine-131 treatment,the control group was given anti thyroid function of drug treatment.The efficacy and adverse drug reaction of the occurrence of long-term and short-term in the two groups were compared. Results In the observation group,the cure rate and total effective rate were respectively 93.48% and 100.00%,which were significantly higher than the control group for 63.04% and 84.78%(χ2= 12.55,7.57,all P< 0.05).The incidence of adverse reaction in the observation group was 4.35%,which was significantly lower than 21.74% in the control group(χ2= 6.13,P< 0.05).The recurrence and complication(hypothyroidism) cases in the observation group,were 1 cases and 8 cases,while the control group were 10 cases and 1 cases.The relapse rate of the observation group was significantly lower than that of the control group,and the incidence of complications was significantly higher than the control group,the difference was statistically significant(χ2= 8.36,6.03,all P< 0.05). Conclusion The iodine short-term efficacy of-131 in treatment of hyperthyroidism can significantly improve the treatment of the disease,and has high safety,but the complication rate is higher than that of anti thyroid drugs. Key words: Hyperthyroidism; Iodine radioisotops