Effects of combination of traditional Chinese and Western medicine in treatment of schizophrenia

Abstract

Objective To evaluate the clinical efficacy and safety of combined therapy of Chinese and Western medicine in the treatment of schizophrenia. Methods According to the digital table,130 patients with schizophrenia were randomly divided into the observation group and control group, with 65 cases in each group. The control group was treated with perphenazine and other Western medicine treatment, the observation group was treated based on the control group with Jieyu Kaiqiao pill added, The clinical curative effect, PANSS score and adverse drug reaction of both groups were compared. Results In the observation group, the total effective rate was 96.92%,significantly higher than that of the control group(72.31%);After treatment, PANSS score of observation group was(42.68±6.11), while it was(55.12±6.45)in control group. The PANSSscores of both groups were significantly lower than that before treatment, PANSS score of observation group was significantly lower than that of the control group, there was significant difference between groups(t=6.61,P<0.05);the incidence of adverse reaction of the observation group was 10.77%,significantly lower than the control group(58.46%); the difference was statistically significant (χ2=32.66,P<0.05). Conclusion Jieyu Kaiqiao pill combined with Western medicine for the treatment of schizophrenia can significantly improve the clinical efficacy, reduce the incidence of adverse drug reactions. Key words: Schizophrenia; Combine traditional Chinese and Western medicine; Jieyu Kaiqiao pill; Efficacy; Safety