The influences of metoprolol in the treatment of diastolic blood pressure on blood sugar

Abstract

Objective To explore the influences of metoprolol in the treatment of diastolic blood pressure on blood glucose.Methods 120 patients with diastolic blood pressure were selected and divided into the research group and the control group,each group 60 cases.The research group was given metoprolol,and the control group was given pelodipine.The treatment time was 12 months.In treatment process,bload glucose and pressure was regularly detected and compared between the two groups.Results After treatment,the diastolic blood pressure of the two groups was lower than that before treatmen(all P ＜ 0.05),but the difference of the diastolic blood pressure between the two groups had no statistical significance before and after treatment(all P ＞ 0.05).The fasting blood glucose(GLU),P2hPG(P2hPG) of the two groups in 1,3,6 months had no obvious difference with those before treatment,but after 12 months the treatment,P2hPG,GLU of the research group was(6.23±0.89) mmol/L,(7.46±0.71) mmoL/L,respectively,and was higher than those before treatment[(4.97±0.52) mmol/L,(5.21±0.69) mmol/L]and those of the control group at the same period[(5.13±0.48)mmol/L,(5.16±0.67) mmol/L(all P＜0.05).Conclusion Metoprolol in the treatment of diastolic blood pressure had good effect.Long term use of drugs(1 year or more) could increase blood glucose levels,but had no other clinical damage,and the safety was good. Key words: Metoprolol; Hypertension; Blood glucose