The effect of bupivacaine single use or combined with sufentanil for pregnant woman in caesarean operation with chills and pain

Abstract

Objective To observe and explore the effect of bupivacaine (BUP) single use or combined with sufentanil (SUF) for pregnant woman in caesarean operation with chills and pain. Methods 96 pregnant women with caesarean section were selected, they were randomly divided into observation group and control group by random number method, each group with 48 cases.Patients in the observation group accepted BUP combined with SUF treatment, while the control group only received BUP treatment.The intraoperative and postoperative data of maternal chills and dragging pain, and the incidence of adverse reactions were compared between the two groups. Results The sensory block onset time and duration of the observation group were (1.7±0.5)min and (126.2±9.5)min, which in the control group were (2.0±0.4)min and (9.1±11.0)min, the differences between the two groups were statistically significant (t=2.295, 15.88, all P<0.05).For chills and stretch of pregnant women, the number of the observation group were 2 casesand 3cases, which in the control group were 9cases and 10cases, the differences between the two groups were statistically significant (χ2=5.031, 4.360, all P<0.05).No patient had toxicity of local anesthetics between two groups.Total anesthesia effective rate of the observation group was 97.9%, which of the control group was 83.3%, the total anesthesia effect of the observation group was better than the control group (χ2=4.414, P<0.01). Conclusion BUP combined with SUF treatment has significant effect for pregnant women in caesarean operation, as well as can significantly relieve the pregnant women' chills and pain. Key words: Bupivacaine; Sufentanil; Cesarean section