The effect of amiodarone combined with beta blocker on cardiac function in patients with acute myocardial infarction complicated with rapid arrhythmia

Abstract

Objective To investigate the effect of amiodarone combined with beta blocker on cardiac function in patients with acute myocardial infarction complicated with rapid arrhythmia. Methods 108 cases of acute myocardial infarction complicated with rapid arrhythmia in our hospital from June 2014 to October 2015 were randomly divided into observation group and control group, 54 cases in each group. Control group was treated with amiodarone, observation group was treated with amiodarone combined with beta blocker (metoprolol). Recorded left ventricular end diastolic diameter (LVEDD), left ventricular end systolic diameter (LVESD), ejection fraction (LVEF), and heart rate (HR) of two groups before and after treatment, compared the indexes of cardiac function and clinical curative effect. Results The total effective rate in control group was 79.63%, significantly lower than 96.30% in observation group, with statistically significant difference between two groups (P 0.05); after treatment, LVEDD, LVESD, and HR in observation group were significantly lower than those in control group, LVEF was significantly higher than that in control group, with statistically significant differences between two groups (P<0.05). Conclusion The effect of amiodarone combined with beta blocker on cardiac function in patients with acute myocardial infarction complicated with rapid arrhythmia is significant, which can significantly improve the clinical treatment effect and the cardiac function of patients. Key words: Amiodarone; Beta blocker; Acute myocardial infarction; Arrhythmia; Cardiac function