The detection and significance of serum enzymes in the adult with central nervous system infections

Abstract

Objective To study the serum enzyme in the adult central nervous system infection in patients and its clinical significance,aimed at providing basis for the diagnosis and prognosis of the adult central nervous system infection. Methods 68 patients with central nervous system infections were treated in June 2008 to Decem 2009 in Neurology Department of our hospital. In addition, 60 healthy persons were selected at the same time as control group. Serum aspartate aminotransferase ( AST), lactate dehydrogenase ( LDH) , Creatine kinase ( CK) , CK-MB ( CK-MB)levels were detected. Results AST,LDH,CK and CK-MB levels of the central nervous system infection group were higher than the control group,and the difference between the two groups was statistically significant(P<0.05). Severe group AST, LDH, CK and CK-MB and other content of the four enzymes were higher, and the difference between the two groups is also significant ( P < 0.05 ). Conclusions Adult patients with central nervous system infection significantly increased serum enzyme levels, and serum enzyme levels had a positive correlation with the severity. Serum enzyme was a reliable adult central nervous system infections diagnostic index. Key words: Central nervous system infections; Aspartate aminotransferases; L-lactate dehydrogenase; Creatine kinase