Abstract

Accurate staging is of importance for taking appropriate management decisions in a patient with newly diagnosed breast cancer. The role of 18FDG-imaging in detecting extra-axillary lymph node involvement and distant lesions in high-risk breast cancer patients is highlighted. This review also discusses potential roles of 18FDG-PET/CT in early assessing response to neoadjuvant chemotherapy. Interim-PET/CT received increased attention in recent years through pilot studies exploring its role in specific subtypes of breast cancer. Results of a French trial that used early metabolic response with 18FDG-PET/CT as a means to select poor responders for intensification have been recently published, with encouraging results.

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