Synthesis of Imidazo [1, 2-a] Pyridine Derivatives Using Copper Silicate as an Efficient and Reusable Catalyst

Abstract

Synthesis of imidazo [1, 2-a] pyridines derivatives were reported from 2-aminopyridine and various substituted phenacyl bromide using copper silicate as an efficient, eco-friendly, and reusable catalyst. The present protocol offers various advantages, such as the use of less hazardous solvent, high yield, and operationally simple procedure.