Abstract
Silver nanoparticles (AgNPs) have provided a broad spectrum of antiviral activity against some types of enveloped and non-enveloped viruses. Silver nanoparticles are currently the most widely commercialized nanomaterials. In recent times, viral infections are emerging as one of the most common diseases with high mortality in the human population. The present study investigates the antiviral efficacy of the silver nanoparticles synthesized by the green method against HSV-1 and H1N1 influenza viruses. Characterization studies revealed that the silver nanoparticles showed an average particle size of 47 nm with a surface plasmon resonance peak at 426 nm. Silver nanoparticles exhibited 50% cytotoxicity in Vero cells at 197 µg/mL concentration, and 50% Inhibitory concentration (IC50) against HSV-1 was observed at 19.6 μg/mL. Silver nanoparticles demonstrated > 1 log reduction in H1N1 influenza A virus at 17 µg/mL. These findings indicate that silver nanoparticles possess excellent antiviral activity, which can be suitably used in various formulations to eradicate the spread of viral infections.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
