Abstract

In the scientific field, microbial contaminations are growing along with the developments of newer research methodologies. Evaluating anti-microbial activity using newly designed materials has been gaining importance over the years to address this issue. The present work aims to form zinc stannate nanoparticles (ZTO NPs) through bio-synthesis and compare their biological efficiency with the as-synthesized nanoparticles through chemical synthesis. The nanoparticles (Zn2SnO4) were synthesized through a hydrothermal method by developing moderate experimental conditions. Three different combinations were synthesized using 2:1 mole ratio of ZnCl2 and SnCl2 precursors, and leaf extracts such as Aloe barbadensis mill and Terminalia catappa were used in the bio-synthesis method. Sodium hydroxide was used as a mineralizer in the chemical synthesis method. The obtained ZTO NPs were characterized by XRD, SEM-EDS, and UV-Visible spectral techniques. Finally, the antibacterial and anti-fungal activities were evaluated using the Agar-well diffusion method. Competitive biological activity response from the bio-synthesized ZTO NPs against the selected bacterial (Bacillus subtilis, S. Aureus, E. Coli, and P. Aeruginosa) and fungal strains (A. Niger and C. albicans). The synthesized ZTO NPs were highly efficient in exhibiting potential biological activity against the selected microbes.

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