Abstract
A convenient route to the synthesis of pyrazolo[3,4-b]pyridin-3-ones via condensation of 3- amino-1-phenylpyrazolin-5-one with 4-hydroxy-6-methylpyran-2-one. The isomeric pyrazolo[3,4-b]pyridin-3-ones obtained are functionalized in position 4 or 6 by aliphatic and aromatic amines, on the other hand position 1 of another derivative pyrazolopyridinic was functionalized by a synthetic grouping. The serotoninergic activity of the various compounds obtained was also examined and discussed.
Published Version
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