Abstract
To explore the role of Galacto-oligosaccharide (GOS) in preventing constipation and promoting excretion of feces. The high, medium and low doses of GOS-1000-S (8.8g/kg, 4.4g/kg, 2.2g/kg) were administered orally to constipation mice for 7 days, and then we measured the propulsive rate of intestines, first defecation time, the number of feces particle and fecal weight in 5 hours. The results showed that GOS-1000-S can significantly promote the small bowel propulsion, shorten the first defecation time and increase the fecal weight number of fecal particle of constipation mice. These indicate that GOS has the effect of relieving constipation and defecating feces excretion. This study provided a basis for the development of GOS with constipation-relieving functions as a health supplement.
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