Abstract
Purpose: To evaluate the efficacy of auto simple limbal epithelial transplantation (SLET) and alloSLET in patients with different causes of limbal stem cell deficiency (LSCD).Study Type: Single-center prospective interventional study.Materials and Methods: Patients visiting tertiary referral hospital between April 2019 and March 2020 satisfying the criteria for labeling LSCD, also inclusion and exclusion criteria were enrolled.Results: Thirty-one eyes of 31 patients (20 men, 11 women) underwent SLET surgery (15 autoSLET, 16 alloSLET). The most common etiology in patients undergone SLET was chemical injury (11, 35.5%) followed by Stevens–Johnson syndrome/Toxic Epidermal Necrolysis (SJS/TEN) (9, 29.0%). SJS/TEN was the most common cause of bilateral LSCD. Combined successful outcome of autoSLET and alloSLET was 64.5%.Conclusion: SLET is a simple, useful surgery to restore LSC and it does not require any specialized center and can be done in a center with limited resources.
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