Role of Autologous Platelet Rich Plasms (Aprp) In the Take of Full Thickness Skin Graft in Post Burn Contracture

Abstract

All deeper burns especially second degree deep dermal and full thickness heals by scarring that causes restrictions in the movements and aesthetics issues for patients. Burn reconstructive surgery requires that the defects after release should be replaced with donor tissues which have matching texture and colour like autologous skin grafting or flap surgeries. Autologous platelet rich plasma contains concentrated platelets after graded centrifugation, which has various applications like alopecia, acne, reproductive techniques etc. Here we are using this method to test for role in take of Full Thickness Skin Graft post burn contracture. Full-thickness skin grafts include full thickness of the epidermis and dermis whereas split-thickness skin grafts include the entire epidermis and only partial dermis. The main complication of this procedure is risk of graft failure. Autologous platelet-rich plasma (APRP) as the name suggests is concentration of the patient’s own platelets in a small amount of plasma. It is enriched by growth factors, and it acts as a fibrin sealant and has various properties. Its important application is in skin grafting where it aids as a fibrin sealant and aids in the take of the graft by enriching it with growth factors and promoting angiogenesis The purpose of this case report is using autologous platelet rich plasma as a therapeutic method for accelerating take of Full Thickness Skin Graft in post burn contracture with better prognosis.