Abstract
The aim of this research was to study of stability of the basic physico-chemical and pharmaco-technological indexes of quality (appearance, average mass, homogeneity of mass, resistance to crushing, erosion, decomposition, identification and quantitative determination of amino acids) obtained samples of tablets based on the swine’s cryoliophilized xenoderma with lecithin and without it. The results of study samples of drugs fit into acceptable standards and show the stability of the main quality indicators during three years of storage at a temperature (8-10)° C in a tightly closed containers in a place protected from light.
Highlights
Nowadays the pharmaceutical market offers a number of medicines with immunostimulatory and immunoprotective pharmacological activity. [3,16] In the complex treatment of this pathology, in addition to etiotropic therapy, the polypropylenic drugs of symptomatic action are widely used
The aim of this research was to study of stability of the basic physico-chemical and pharmaco-technological indexes of quality obtained samples of tablets based on the swine’s cryoliophilized xenoderma with lecithin and without it
The results of study samples of drugs fit into acceptable standards and show the stability of the main quality indicators during three years of storage at a temperature (8-10)° C in a tightly closed containers in a place protected from light
Summary
Nowadays the pharmaceutical market offers a number of medicines with immunostimulatory and immunoprotective pharmacological activity. [3,16] In the complex treatment of this pathology, in addition to etiotropic therapy, the polypropylenic drugs of symptomatic action are widely used. [3,16] In the complex treatment of this pathology, in addition to etiotropic therapy, the polypropylenic drugs of symptomatic action are widely used. The majority of these drugs contain active pharmaceutical ingredients (APhIs) of chemical origin. Organopreparations complement the deficiency of cellular biomolecules, eliminate various "cellular defects" at the cellular level, due to the effect of organotropy improve the processes of physiological regeneration in the appropriate organs of the patient. This leads to a normal renovation of organs and tissues and theirs physiological functions. Bihuniak (LLC "Institute of Biomedical Technologies", Ternopil) has developed a dietary supplement "Xenoderm", which contains natural complexes of peptides, amino acids, micro-and macro elements, nucleotides, growth factors, etc. [13,14] Such dietary supplement cause a wide range of pharmacological activity, : antihistamines, antiallergic, membrane-protector, anti-toxic and antimicrobial effects in allergic diseases; stimulate the effective healing of wounds and ulcers; improves the functioning of the digestive system; has the properties of a natural adsorbent. [2,6,7]
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