Abstract
<p>Acute myeloid leukemia (AML) with <em>CBFB-MYH11</em> fusion gene is almost always associated with either inv(16)(p13.1q22) or t(16;16)(p13.1;q22). Only a few variants leading to formation of this chimeric gene have been reported. In this report, we describe a novel type of <em>CBFB-MYH11</em> fusion variant generated by an insertion of <em>CBFB</em> into the <em>MYH11</em> gene, which is identifiable by fluorescence <em>in situ</em> hybridization (FISH).</p>
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