Primary sudden cardiac death prevention in hypertrophic cardiomyopathy resulted from LEOPARD Syndrome

Abstract

Leopard syndrome is an autosomal dominant inherited disease manifested by numerous cutaneous birthmarks, heart electrical conduction disorders, hypertelorism, pulmonary valve stenosis, deafness and hypertrophic cardiomyopathy. The disease may be accompanied by symptomatic ventricular tachycardia. In patients without the need for cardiac pacing and indications for a cardioverter-defibrillator (ICD) implantation, a completely subcutaneous system (S-ICD) may become an efficient option.