Abstract
Primary breast lymphoma is a rare disease, which accounts for 0.4% of all malignancies seen in the breast and 2% of extranodal lymphomas. The majority of cases are B-cell lymphomas, with diffuse large cell (B) lymphoma the predominant histological type. A variety of treatment modalities have been suggested, with radiation therapy recommended for stage I patients and chemotherapy recommended for stage II patients. Outcome following treatment is predicted by the pathological grade of the tumor and the presence of lymph node involvement. Radical surgical resection including mastectomy has not been shown to affect the outcome of this entity.
 A 61-year-old woman presented with a one month history of a painful right breast lump. Examination identified the presence of two lumps which were biopsied, confirming the presence of a lymphocytic lymphoma expressing a B-cell phenotype with co-expression of CD 43 (MT-1) consistent with MALT-type lymphoma.
 She underwent further excision for recurrent tumor but declined adjuvant therapy. She has remained disease free during a 7-year follow up period.
 Primary breast lymphoma is a rare malignancy of the breast representing less than 2% of non-Hodgkin lymphoma. The features on clinical breast examination and imaging are not characteristic and cannot be differentiated from breast carcinoma. Treatment involves surgical resection with adjuvant chemotherapy and radiotherapy administered in selected cases.
 A 61-year-old woman presented with a one month history of a painful right breast lump. Examination identified the presence of two lumps which were biopsied, confirming the presence of a lymphocytic lymphoma expressing a B-cell phenotype with co-expression of CD 43 (MT-1) consistent with MALT-type lymphoma.
 She underwent further excision for recurrent tumor but declined adjuvant therapy. She has remained disease free during a 7-year follow up period.
 Primary breast lymphoma is a rare malignancy of the breast representing less than 2% of non-Hodgkin lymphoma. The features on clinical breast examination and imaging are not characteristic and cannot be differentiated from breast carcinoma. Treatment involves surgical resection with adjuvant chemotherapy and radiotherapy administered in selected cases.
Highlights
Primary breast lymphoma is a rare malignant lesion of the breast representing less than 0.5% of all malignant neoplasms of the breast and 1% to 2% of all non-Hodgkin lymphomas. (1) Few cases are reported in the literature, mainly small case series and retrospective reviews
Primary breast lymphoma is a rare malignancy of the breast representing less than 2% of non-Hodgkin lymphoma
The description proposed by Wiseman and Liao refers to two stages only, namely Stage I and stage II with the exclusion of tumors that may have originated from other sites outside of the breast
Summary
Primary breast lymphoma is a rare malignant lesion of the breast representing less than 0.5% of all malignant neoplasms of the breast and 1% to 2% of all non-Hodgkin lymphomas. (1) Few cases are reported in the literature, mainly small case series and retrospective reviews. Treatment strategies include a range of modalities with surgery, radiotherapy and chemotherapy being the most commonly used
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
