Abstract

Primary breast lymphoma (PBL) is a rare form of extranodal non-Hodgkin lymphoma, with breast mass as the main symptom, with or without local lymphadenpathy, and it shows metastatic features and poor prognosis. Diffuse large B-cell lymphoma is the most common pathological pattern, other forms like follicular lymphoma is less common. There is no consensus on prognostic factor and first-line treatment plan at present. In this review, we describe the pathogenesis, staging, risk stratification, prognosis, and treatment advances of primary breast diffuse large B cell lymphoma (PB-DLBCL). Key words: Lymphoma, large B-cell, diffuse; Breast neoplasms; Review

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