Possible discoid lupus erythematosus in newborn infant; report of a case with subsequent development of acute systemic lupus erythematosus in mother.

Abstract

THE the scalp and face, which clinically and histologically was consistent with chronic discoid lupus erythematosus, and of his mother, who developed acute disseminate lupus erythematosus 11 months later. REPORT OF CASES Case 1.— J. V., a 6-week-old white boy, was first seen on Nov. 3, 1951. The referring physician stated that an eruption was present at delivery but had become more livid, and the number of lesions had increased in the six weeks since birth. Gestation period had been full term and normal. Birth weight was 4 lb. 13 oz. (2,183 gm.), length, 18 in. (46 cm.). Physical examination was negative except for the skin of the scalp and face, which showed discrete, erythematous macules varying from 0.5 to 3.0 cm. in diameter. Scaling, follicular plugging, and atrophy were definite (Fig. 1). Histologic examination of a scalp lesion showed relative and absolute hyperkeratosis, keratotic plugging, alternate areas of atrophy