Abstract
Hybrid positron emission tomography (PET)-MRI imaging enable the acquisition of functional information by PET, and structural as well as functional information by MRI. The two modalities are complementary: PET offers unparalleled sensitivity to molecular events, e.g. occupation of receptors, activity of glucose metabolism, during tumor or inflammation; while MRI offers high soft tissue contrast (including in highly mobile structures such as the heart) and other information (diffusion, blood flow, spectroscopy). Simultaneous acquisition is crucial for understanding brain function, the pathophysiology of cancer, mechanic cardiovascular dysfunction, and disorders of nutrition and metabolism.
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