Abstract
Outcomes of Severe Sepsis among Adults in a Tertiary Care Hospital in Kolkata - A PreliminaryStudy
Highlights
A prospective, observational study was conducted in the intensive therapy units (ITU) of an urban tertiary care hospital in Kolkata, India to determine the clinical Association between outcomes and other factors of severe sepsis among adult patients
In a study based on 1995 hospital discharge data, Angus et al [5] estimated that >750,000 cases of severe sepsis occur in the United States annually
It must be recognized that sepsis and severe sepsis are treated/managed in a variety of ITUS and hospital settings which makes potential “between-ITU variance” an important parameter that may be a major determinant of outcome differences
Summary
A prospective, observational study was conducted in the intensive therapy units (ITU) of an urban tertiary care hospital in Kolkata, India to determine the clinical Association between outcomes and other factors of severe sepsis among adult patients. Sepsis is a major worldwide cause of morbidity and mortality [2] and causes a large burden of disease with negative impact in the community It is an important cause of admission in the intensive care units (ICU) probably due to more severe illnesses of hospitalized patients and to the persistently high incidence of nosocomial infections. In a study based on 1995 hospital discharge data, Angus et al [5] estimated that >750,000 cases of severe sepsis occur in the United States annually This is significantly greater than the incidences of the other well recognized diseases such as congestive heart failure [6], death due to cancer of the breast, colon [7], or AIDS [8]. Despite better understanding of sepsis pathophysiology and improved management through multiple modalities, the incidence continues to increase and fatality rates remain unacceptably high
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