Abstract
Purpose: To compare enhanced depth imaging (EDI) and non-EDI swept source optical coherence tomography (SS-OCT) in their ability to capture the suprachoroidal space (SCS).
 Materials and methods: Twenty volunteers with a minimum age of 18 years without any ocular pathology and refractive error below Å} 2 diopters underwent SS-OCT foveal scanning, with and without EDI. Masked averaged B-scan lines were analyzed for presence of the SCS. When the SCS was seen, the percentage of the scan on which this structure could be unequivocally observed was measured. Scores obtained from the images taken with or without EDI were then compared.
 Results: Thirty-seven eyes were analysed, since three eyes of three different patients were eliminated, as the outer border of the choroid was insufficiently delineated with both modalities. The SCS was not detected at all on 14 pictures (37.8%) obtained by non-EDI SS-OCT and 9 pictures (24.3%) obtained by EDI SS-OCT. When the SCS was detected with both modalities, it was observable on 27.2+/-24.2% of the scan without EDI and 40.4+/-30.3 of the scan with EDI (p < .001)
 Conclusions: EDI SS-OCT enables a more frequent and extensive visualization of the suprachoroidal space than non-EDI SS-OCT. This new approach could be considered as the most accurate modality to currently visualize the SCS in vivo.
Highlights
The suprachoroidal space (SCS) is receiving increasing attention as its potential role in the diagnosis and treatment of various retinal conditions is being recognized.[1]Enhanced depth imaging (EDI), a modification of the regular acquisition technique, was originally described for spectral-domain optical coherence tomography (SD-OCT) in order to improve visualization of deeper structures within the choroid.[2]
There are, limitations in the ability of enhanced depth imaging (EDI) SD-OCT to capture details of the outer choroidal border.3,4On the other hand, the SCS has been captured in health and disease by using swept-source OCT (SS-OCT).[5]
SCS was not detected in 14 pictures (37.8%) obtained by non-EDI SS-OCT and 9 pictures (24.3%) obtained by EDI SS-OCT
Summary
The suprachoroidal space (SCS) is receiving increasing attention as its potential role in the diagnosis and treatment of various retinal conditions is being recognized.[1]. Enhanced depth imaging (EDI), a modification of the regular acquisition technique, was originally described for spectral-domain optical coherence tomography (SD-OCT) in order to improve visualization of deeper structures within the choroid.[2] EDI improved visualization of the choroidoscleral interface. There are, limitations in the ability of EDI SD-OCT to capture details of the outer choroidal border.3,4On the other hand, the SCS has been captured in health and disease by using swept-source OCT (SS-OCT).[5]. We aim to compare non-EDI and EDI-OCT in their ability to capture the SCS in healthy subjects and thereby attempt to improve the visualization of such an important structure. When the SCS is seen, we aim to quantify on what percentage of the macular scan it is patent and draw a comparison between both imaging approaches
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