Abstract
BackgroundWe evaluated subfoveal choroidal thickness measured with two different forms of optical coherence tomography (OCT), enhanced-depth imaging (EDI) and swept-source (SS) OCT, in central serous chorioretinopathy (CSC).MethodsFifty-six eyes of 48 patients diagnosed with acute or chronic CSC, were studied prospectively. Subfoveal choroidal thickness was measured as the distance between the outer border of the retinal pigment epithelium-Bruch’s membrane complex, and the chorioscleral border under the fovea. Subfoveal choroidal thickness was measured using EDI-OCT and SS-OCT. We also measured serous retinal detachment (SRD) only with SS-OCT. The Pearson correlation coefficient was used to assess the correlation between subfoveal choroidal thickness values determined by the two different OCT modalities.ResultsThe mean patient age was 52 ± 13 years (range, 32–82 years). Among the 56 eyes, 21 had acute CSC and 35 had chronic CSC. Subfoveal choroidal thickness measured with EDI-OCT was 336.6 ± 91.6 μm in acute and 388.0 ± 103.4 μm in chronic CSC. With SS-OCT, the thickness in acute CSC was 332.0 ± 96.7 μm and that in chronic CSC was 392.6 ± 101.3 μm. Acute CSC (p <0.001, correlation coefficient; r = 0.99) and chronic CSC (p <0.001, correlation coefficient; r = 0.97) values obtained with the two different OCT modalities correlated significantly. Among the 56 eyes, 43 (19 eyes with acute and 24 with chronic CSC) were evaluable for SRD height by SS-OCT. The mean SRD height was 128.9 ± 83.6 μm in acute cases and 96.3 ± 62.0 μm in chronic cases.ConclusionsSubfoveal choroidal thickness obtained with two different OCT modalities correlated significantly.
Highlights
We evaluated subfoveal choroidal thickness measured with two different forms of optical coherence tomography (OCT), enhanced-depth imaging (EDI) and swept-source (SS) OCT, in central serous chorioretinopathy (CSC)
Enhanced depth imaging (EDI) OCT is a recent modification of the standard technique
The EDIOCT modality places the objective lens of the spectraldomain optical coherence tomography (SD-OCT) closer to the eye, such that the light backscattered from the choroid is closer to the zero-delay and sensitivity is thereby enhanced
Summary
We evaluated subfoveal choroidal thickness measured with two different forms of optical coherence tomography (OCT), enhanced-depth imaging (EDI) and swept-source (SS) OCT, in central serous chorioretinopathy (CSC). Choroidal vascular hyper-permeability is frequently seen in eyes with CSC This raises hydrostatic pressure in the choroid and thereby increases choroidal thickness [3,4]. In recent years, detecting the choroid using spectraldomain optical coherence tomography (SD-OCT) has Enhanced depth imaging (EDI) OCT is a recent modification of the standard technique. This novel modality shows the cross-sectional structure and thickness of the choroid using commercial SD-OCTs. Basically, the EDIOCT modality places the objective lens of the SD-OCT closer to the eye, such that the light backscattered from the choroid is closer to the zero-delay and sensitivity is thereby enhanced. This modality produces better imaging of the choroid [8,9]
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