Observation of curative effect of budesonide combined with terbutaline aerosol inhalation in the treatment of acute asthma

Abstract

Objective To investigate the efficacy of budesonide combined with terbutaline atomization inhalation in the treatment of acute asthma attacks, and to provide reference for clinical treatment. Methods 118 patients with acute asthma attack were selected and randomly divided into observation group and control group, 59 cases in each group.The control group was treated with budesonide inhalation, the observation group was treated with budesonide combined with terbutaline aerosol inhalation The clinical efficacy of the two groups, clinical symptoms and signs of the disappearance time were compared, the pulmonary function test results and the occurrence of adverse reactions were compared. Results In the observation group, the total effective rate was 72.88%, which was significantly higher than 52.54% of the control group (χ2=5.218, P<0.05). The disappear time of shortness breath, cough, pulmonary rales in the observation group were (4.01±1.42)d, (6.58±1.51)d, (7.02±227)d, which were significantly shorter than (5.71±1.59)d, (8.52±1.97)d, (8.69±2.61)d in the control group (t=4.557, 4.421, 4.659, all P<0.05). After treatment, the FEV1, FVC and peak expiratory flow (PEF) of the observation group were (2.35±0.67)L, (2.76±0.62)L, (2.91±0.49)L, which were significantly higher than(2.09±0.57)L, (2.31±0.51)L, (2.48±0.59)L of the control group (t=3.625, 3.641, 3.887, all P<0.05). The two groups had no serious adverse reactions. Conclusion Budesonide combined with terbutaline atomization inhalation can relieve the clinical symptoms of patients with acute asthma, improve lung function, improve the clinical treatment effect and has good security. Key words: Asthma; Budesonide; Terbutaline