Abstract
The current research focuses on the numerical simulation to scrutinize the divergent flow characteristics in a stirred tank bioreactor. The reactor is composed of a cylindrical flat-bottom tank equipped with two Rushton six-blade impellers and four baffles on the wall of the tank. The turbulent flow within the reactor is modeled with the Large Eddy Simulation model. The traditional subgrid model of Smagorinsky was used to solve turbulent small-scale structures with Smagorinsky constant C s = 0.1 The influence of the reactor components (i.e., cylindrical wall, baffles, shaft, and Rushton turbines) on the liquid-flow field has been obtained using the immersed boundary method. A highly parallelized computer code is developed to perform the simulation on a multi-core Graphics Processing Unit platform. The results are demonstrated in phase average flow velocities and turbulent statistics, with validation from the available experimental data reported in the literature.
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