Abstract
Cow's milk protein allergy (CMPA) is the most common food allergy in young children. A 40-day-old boy on regular formula presented with generalized edema and chronic watery diarrhea since birth. Laboratory data revealed serum albumin at 0.9 g/dL, and urine analysis did not reveal proteinuria. Echocardiogram was normal. CMPA was diagnosed based on history and rapid response to amino-acid-based infant formula (Neocate®). At the infant’s last follow-up examination at 24 months, he was thriving on a regular diet, with normal growth.
Highlights
Cow’s milk protein allergy (CMPA) is the most common food allergy in infants and young children and has a prevalence of 2% - 3% in the general population [1]
Cow's milk protein allergy (CMPA) may present with severe hypoalbuminemia [4,5]
We report an unusual presentation of non-IgE CMPA in a small infant with severe hypoalbuminemia and chronic diarrhea
Summary
Cow’s milk protein allergy (CMPA) is the most common food allergy in infants and young children and has a prevalence of 2% - 3% in the general population [1]. We report an unusual presentation of non-IgE CMPA in a small infant with severe hypoalbuminemia and chronic diarrhea. A 40-day-old boy was admitted to the hospital with chronic diarrhea since birth (i.e., from day 1) and generalized edema of the whole body (anasarca), which developed in the 3rd week of life. He had watery, non-bloody diarrhea four times per day. Annex Publishers | www.annexpublishers.com of overfeeding and no cardiac symptoms His prenatal, natal, and postnatal history revealed normal vaginal delivery, full term, no neonatal intensive care admission, and other parts of his history were not significant. At the last follow-up examination at 24 months, he was thriving on a regular diet with normal growth
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