Symptoms and signs not clearly related to infant cow's milk protein allergy

Abstract

Listen

Translate article

Objective To improve the understanding of infant cow's milk protein allergy analyzing the symptoms and signs in infants caused by cow’s milk protein allergy and have not raised clinical attention, such as dark circles, night sweat, pillow baldness, nocturnal molar, and recurrent oral ulcer. Methods 89 infants diagnosed as cow's milk protein allergy were selected as a study group, and 87 healthy infants a control group. A questionnaire designed for dark circles, night sweat, pillow baldness, nocturnal molar, and recurrent oral ulcer was answered by the two groups; and statistical analysis was performed. Results The proportions of dark circles, night sweat, and pillow baldness were significantly higher in study group than in the control group [50.56% (45/89) vs. 8.05% (7/87), 31.46% (28/89) vs. 16.09% (14/87), and 29.21% (26/89) vs. 12.64% (11/87)]. There were no statistical differences in the incidences of nocturnal molar and recurrent oral ulcer between these two groups (both P>0.05). Conclusions Infants with cow's milk protein allergy are more prone to dark circles, night sweat, and baldness, suggesting that these may be symptoms of cow's milk protein allergy. Whether night molar and recurrent oral ulcer are related to cow's milk protein allergy in infants is uncleared. Key words: Cow's milk protein allergy; Dark circles; Night sweat; Pillow baldness; Infants