Abstract
Idiopathic Pulmonary Hemosiderosis in a Middle-Aged Woman: a Case Report
Highlights
Idiopathic pulmonary hemosiderosis (IPH) extremely rarely occurrs in adults according to current literature.We report one case of IPH in a middle-aged woman presenting with extensive central-predominant ground glass opacities and consolidation in the lungs
Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder characterized by recurrent episodes of unexplained intra-alveolar hemorrhage, followed by accumulation of hemosiderin in macrophages
To deepen the understanding of this disorder, we report one case of IPH in an adult confirmed by transbronchial lung biopsy (TBLB) and review relevant literature
Summary
Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder characterized by recurrent episodes of unexplained intra-alveolar hemorrhage, followed by accumulation of hemosiderin in macrophages. A 47-year-old woman had a 3-month history of cough, sputum, and hemoptysis symptoms, which occurred 3 to 4 times per day with a blood loss of 5 ml each time. She was treated empirically with broad-spectrum antibiotics after being suspected of a nonspecific infection. Perihilar, and lower lobe regions, non-enhanced axial and coronal chest CT images revealed significant central groundglass opacities and consolidation. After three days of antibiotic treatment, the lesions had progressed significantly (Figures 2a and b). Based on the patient's symptoms, signs, and laboratory tests, idiopathic pulmonary hemosiderosis (IPH) was diagnosed, and the patient was given hormone and immunosuppressive therapy. The lesions were visibly absorbed after one week of treatment and vanished after two weeks (Figures 3a and b)
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