Non-specific chronic vaginites in women of the industrial center and ways of their correction

Abstract

Insufficient effectiveness of antibacterial and anti­inflammatory therapy dictates the need to find new ways of prevention and treatment of chronic recurrent inflammatory diseases of the vagina and cervix in women with the use of new generation multiprobiotics. Objective of the study: evaluation of the effectiveness of the use of a multipropiotic drug with propolis in the treatment of recurrent bacterial vaginitis in women of reproductive age - residents of a large industrial city. Materials and methods of the study: 69 patients aged 18 - 45 years with bacterial vaginitis living in the large industrial city of Zaporizhzhya were observed. The main group consisted of 14 women with inflammatory diseases of the vagina and cervix, who received in the complex treatment of multiprobiotics with propolis 1 dose 1 time a day in the vagina for 5 days. To determine the presence of an infec­tious agent, microscopic and bacteriological examination of vaginal and cervical canal secretions was performed, the species composition of pathogens was determined by PCR. Results of the study and their discussion. In patients with chronic vaginitis of reproductive age living in the conditions of a large industrial city there are pro­found disorders of the relationship between obligate and pathogenic microorganisms, which contributes to the re­currence of the pathological process. Conclusions. The use of a multiprobiotic drug with propolis, which has a broad antiviral and antibacterial properties, containing bifido, lacto, propionic acid bacteria and propolis can ef­fectively normalize the vaginal microflora in chronic vagi­nitis, shorten the development time and treatment. The results of the study give us grounds to recommend the widespread use of a propolis-based multipropiotic drug for women suffering from chronic vaginitis who are not amenable to standard anti-inflammatory therapy.