Peculiarities of microbiological monitoring in the pathological status of the vegina and cervix in women of reproductive age

Abstract

Vulvovaginal and cervical infections are a risk factor of developing purulent inflammatory diseases of the pelvic organs, miscarriage, antenatal and intranatal infections, with frequent pathogens Ureaplasma, Mycoplasma, Gardnerella vaginalis, Bacterioides. Particular importance is given to the mix-infection as a reservoir of a large number of different potentially harmful microorganisms. The purpose of our study was to study the specific composition of microorganisms in women of reproductive age with pathological secretions from the genital tract and to determine the incidence of genitalurea / mycoplasmosis. 54 patients of reproductive age with complaint on itch, heartburn, excessive secretions from the non-slippery genital tract and / or with an unpleasant smell, which were repeated 2 or more times during the year after the treatment, were examined. During gynecological examination, the following diseases were detected in patients: erosion of the cervix in 8 (14.8%) patients, cervicitis in 6 (11.1%), cervical cyst in 2 (3.7%) women, leukoplakia in 3 (5,55%) of the surveyed. According to the results of bacterioscopy, bacterial vaginosis was detected in 4 (7.4%) patients, unspecified bacterial colpitis — 28 (51.8%), vaginal candidiasis — in 17 (31.5%). In cytological screening, CIN I was diagnosed in 9 (16.6%) subjects, CIN II in 4 (7.4%). Analyzing the results of the study conducted by the polymerase chain reaction of HPV-infection was found in 8 (14,8%), ureaplasma — in 14 (25,9%), mycoplasma — in 6 (11,1%) patients. Staphylococcus aureus 105 — 4 (7.4%), Staphylococcus epidermidis 103 — 1 (1.8%), E. coli 105 — 7 (12.9%), Enterococcus, were detected during bacteriological examination of vaginal and cervical extracts. Fecalis 106 — 9 (16.6%), Candida albicans 105 — 6 (11.1%), Clebsiela 106 — 3 (5.5%), Gardnerella vaginalis 107 —11 (20.3%), Streptococcus 106 — 5 (9.2%). Thus, diagnosed high percentage (22.2%) ureaplasmas combination with other types of conditional — pathogenic microorganisms and viruses and cervical pathology (13%), namely the combination of ureaplasma pathogenic microflora was observed in 8 (14.8%) cases of HPV — 6 (11.1%), with mycoplasma, and pathogenic microflora — 5 (9.3%) patients. In general, 35.2% of cases. Assessing the infection of reproductive age women ureaplasma and mycoplasma less with recurrent abnormal discharge from the genital tract after treatment leads to the search and introduction of modern methods of their diagnosis and treatment.