Abstract
From a pancreatic ribonuclease digest of rat-liver tRNA, several minor dinucleotides have been isolated and characterized. The quantitative distribution indicates that some of them, e.g. m 2 2G-ψ and m 2 2G-C ★ ★ For the designations of oligonucleotides the nomenclature proposed by IUPAC-IUB Commission on Biochemical Nomenclature ( cf. Biochim. Biophys. Acta, 108 (1968) 1) was used and for the abbreviations of minor nucleotides the system using small letters for substitutions has been used ( cf. A. H. Sober, Handbook of Biochemistry, The Chemical Rubber Co., Cleveland, 1968, p. H64–65.) , are constituents of more than one tRNA species whereas others, such as Cm-C and ψm-U, occur in less than 1% of all tRNA molecules. Several minor nucleotides have been shown to occur in more than one dinucleotide, whereas others known to occur in considerable amounts in tRNA could not be detected in dinucleotides. An unknown cationic nucleoside is described which was found in two dinucleotides.
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