Abstract

Molecularly imprinted polymers (MIPs) have specific molecular recognition sites for chemical detection.High affinity receptors can increase the sensitivity of sensors/devices. The synthesis of micro- or nanosized MIP's particles is desirable to improve the sensitivity since MIP's particle sizes are inversely proportional to the affinity between receptors and template molecules. To synthesize nano- or microsized MIPs particles, we demonstrate here a novel microfluidic approach, which presents continuous and uniform MIP's particle generation.

Highlights

  • Nanotechnology has enabled the fabrication of more compact and smaller devices to meet our diverse demands in miniaturization

  • Synthesis of new materials for nanoimprinting lithography, soft lithography, microfluidic technique, and plastic electronics is of interest for chemists to expand the scope of current nanotechnology to advanced levels [1,2,3,4,5,6,7,8,9,10,11]

  • We present a microfluidic synthesis of molecularly imprinted polymer (MIP)

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Summary

Research Letter

Imprinted polymers (MIPs) have specific molecular recognition sites for chemical detection.High affinity receptors can increase the sensitivity of sensors/devices. The synthesis of micro- or nanosized MIP’s particles is desirable to improve the sensitivity since MIP’s particle sizes are inversely proportional to the affinity between receptors and template molecules. To synthesize nano- or microsized MIPs particles, we demonstrate here a novel microfluidic approach, which presents continuous and uniform MIP’s particle generation

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