Mécanisme de fixation du 99mTc-HMDP sur les carcinomes urothéliaux calcifiés de vessie

Abstract

We report a case of transitional cell carcinoma of the bladder visualized on a 99mTc-HMDP bone scintigraphy. CT demonstrated irregular tumor of the bladder with curvilinear calcifications on the surface areas and multiple bilateral pulmonary metastases. Bone scintigraphy showed intense uptake corresponding to the bladder tumor and two bone metastases on the left femur. A few days later, the patient underwent retrograde injection of 99mTc-HMDP into the bladder. Imaging made after voiding showed a tumour uptake of the skeletal labelled agent. Through this case report, we debate 99mTc-biphosphonate uptake mechanisms in transitional cell carcinoma.