Abstract
Background: Exercise and dietary modifications help improve energy balance and glucose control. High intensity interval exercise (HIIE) induces an increase in serum brain-derived neurotrophic factor (BDNF) with a corresponding decrease in its precursor (proBDNF). Pro-BDNF, possesses biological activities opposite those of BDNF. However, only few reports on the effect of HIIE on proBDNF compared to extensive studies on the BDNF.
 Methods: Normal, healthy, male adults performed six sessions of HIIE in a span of 2 weeks. Venous blood was collected, from which fasting blood sugar, glycated haemoglobin, serum insulin, BDNF and proBDNF were measured using ELISA. 
 Results: Marked decrease in markers of glycemic control were recorded following the intervention. A reduction in proBDNF and increase in BDNF was also observed post exercise. We found a strong negative relationship between BDNF and FBS post exercise. 
 Conclusion: HIIE reduces BDNF and proBDNF healthy men.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
